152945-46-5Relevant academic research and scientific papers
Studies on isocyanides and related compounds: A novel synthetic route to furan derivatives
Bossio,Marcaccini,Pepino,Torroba
, p. 783 - 785 (1993)
The Passerini reaction between arylglyoxals 1, isocyanides 2, and cyanoacetic acid affords N-substituted 3-aryl-2-cyanoacetoxy-3-oxopropionamides 3, which are cyclized in the presence of triethylamine to give N-substituted-3-aryl-4-cyano-2,5-dihydro-5-oxofuran-2-carboxamides 4.
