Synthesis p. 783 - 785 (1993)
Update date:2022-08-02
Topics:
Bossio
Marcaccini
Pepino
Torroba
The Passerini reaction between arylglyoxals 1, isocyanides 2, and cyanoacetic acid affords N-substituted 3-aryl-2-cyanoacetoxy-3-oxopropionamides 3, which are cyclized in the presence of triethylamine to give N-substituted-3-aryl-4-cyano-2,5-dihydro-5-oxofuran-2-carboxamides 4.
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Doi:10.1021/jo00073a040
(1993)Doi:10.1016/j.biochi.2013.07.010
(2013)Doi:10.1055/s-0032-1317937
(2013)Doi:10.1021/acs.jafc.0c03286
(2020)Doi:10.1039/c3ob41961d
(2014)Doi:10.1080/07328319308018554
(1993)
