152953-22-5Relevant articles and documents
Synthesis and biochemical studies of 7α-substituted androsta-1,4-diene- 3,17-diones as enzyme-activated irreversible inhibitors of aromatase
Ebrahimian,Chen,Brueggemeier
, p. 414 - 422 (1993)
Several 7α-thiosubstituted derivatives of androstenedione have demonstrated effective inhibition of aromatase, the cytochrome P450 enzyme complex responsible for the biosynthesis of estrogens. Introduction of an additional double bond in the A ring result