152983-29-4

Upstream product

• 4381-25-3 (S)-S-methyl-S-phenylsulfoximine 
• 996-50-9 N,N-diethyl-1,1,1-trimethylsilanamine 
• 10416-59-8 N,O-Bis(trimethylsilyl)acetamide 
• 1193-82-4 racemic methyl phenyl sulfoxide 

Downstream Products

• 412272-25-4 (S)-S-tert-butyl-S-phenyl sulfoximine 
• 1027729-93-6 (S)-ethyl [S-phenyl-N-(trimethylsilyl)sulfonimidoyl]acetate 
• 1027731-82-3 (S)-9,9-dimethoxy-2,2-dimethyl-4-phenyl-10-oxa-λ⁴-thia-3-aza-2-silaundec-3-ene 4-oxide 
• 635311-69-2 C₂₆H₄₅NO₂SSi 
• 142809-68-5 (S)-2-methyl-1-(S-phenylsulfonimidoyl)propan-2-ol 

Relevant academic research and scientific papers

Synthesis of (S)-N-(diphenylphosphinyl)-S-methyl-S-phenyl sulfoximide: A new ligand for asymmetric catalysis

The synthesis of (S)-N-(diphenylphosphinyl)-S-methyl-S-phenyl sulfoximide is reported. Preliminary investigations into the use of this novel sulfoximide as a ligand for asymmetric conjugate addition reactions are also described.

SULFOXIMINES AS KINASE INHIBITORS

The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.

24-SULFOXIMINE VITAMIN D3 COMPOUNDS

The present invention provides novel sulfoximine compounds, compositions comprising these compounds and methods of using these compounds as inhibitors of CYP24. In particular, the compounds of the invention are useful for treating diseases which benefit f

Optically active sulfoximines in enantioselective palladium catalysis

Chiral sulfoximine/Pd-complexes catalyze enantioselective allylic alkylations. The corresponding products have been obtained in good yields with moderate enantioselectivities (up to 73% ee). The crystal structure of an allyl/Pd(II)-complex bearing a chelating sulfoximine is reported.

Asymmetric intramolecular Diels-Alder reactions of sulfoximine-activated trienes

A series of N-substituted sulfoximidoyl-1,6,8-nonatrienes and 1,7,9-decatrienes were synthesized and subjected to thermal intramolecular Diels-Alder (IMDA) reactions to give diastereomeric mixtures of substituted bicyclo[4.3.0]nonanes and -[4.4.0]decanes. The reactions showed varying selectivities. Endo/exo selectivity was interpreted in terms of a combination of steric factors and the asynchronous nature of the cycloadditions. Diastereofacial selectivity could be rationalised by considering attack by the diene on the less hindered face of the conformationally extended vinylic sulfoximine dienophile.