142809-68-5

Upstream product

• 89902-44-3 S-methyl-S-phenyl-N-(trimethylsilyl)sulfoximine 
• 67-64-1 acetone 
• 152983-29-4 (+)-(S_S)-S-methyl-S-phenyl-N-(trimethylsilyl)sulfoximine 

Relevant academic research and scientific papers

β-Hydroxysulfoximines in the catalyzed enantioselective reduction of ketones with borane

Optically active β-hydroxysulfoximines catalyze the asymmetric borane reduction of ketones affording secondary alcohols in high yields with good enantioselectivities (up to 93% ee).

Application of β-hydroxysulfoximines in catalytic asymmetric phenyl transfer reactions for the synthesis of diarylmethanols

(Chemical Equation Presented) Enantiomerically enriched diarylmethanols have been prepared by catalyzed asymmetric phenyl transfer reactions onto aromatic aldehydes with use of readily available β-hydroxysulfoximines as catalysts. As the aryl source, combinations of diethylzinc with either diphenylzinc or triphenylborane have been applied affording arylphenylmethanols with up to 93% ee in good yields. Various functionalized aldehydes and heterocyclic substrates are tolerated, yielding synthetically relevant products.