1531-78-8 Usage
General Description
Ethyl 2-chloromethylbenzoate, also known as ethyl α-chlorotoluene carboxylate, is a chemical compound with the molecular formula C10H11ClO2. It is a colorless to pale yellow liquid that is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and fragrances. Ethyl 2-chloromethylbenzoate is a benzyl ester derivative and can be synthesized through the reaction of 2-chloromethylbenzoic acid with ethanol in the presence of a catalyst. It is important to handle this compound with care, as it is considered to be toxic if swallowed or inhaled, and can cause irritation to the skin, eyes, and respiratory system. Additionally, it may have harmful effects on aquatic organisms if released into the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 1531-78-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,3 and 1 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1531-78:
(6*1)+(5*5)+(4*3)+(3*1)+(2*7)+(1*8)=68
68 % 10 = 8
So 1531-78-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H11ClO2/c1-2-13-10(12)9-6-4-3-5-8(9)7-11/h3-6H,2,7H2,1H3
1531-78-8Relevant articles and documents
Silver-Catalyzed C(sp3)-H Chlorination
Ozawa, Jun,Kanai, Motomu
supporting information, p. 1430 - 1433 (2017/03/23)
A silver-catalyzed chlorination of benzylic, tertiary, and secondary C(sp3)-H bonds was developed. The reaction proceeded with as low as 0.2 mol % catalyst loading at room temperature under air atmosphere with synthetically useful functional group compatibility. The regioselectivity and reactivity tendencies suggest that the chlorination proceeded through a radical pathway, but an intermediate alkylsilver species cannot be ruled out.
Process for preparing o-(carboalkoxy)phenylmethanesulfonyl chloride derivatives
-
, (2016/03/01)
A process for preparing an o-(carboalkoxy)phenylmethanesulfonyl chloride derivative of formula (1), wherein: X is chosen from a hydrogen atom, halogen atoms, C1to C6alkyl groups, C1to C6haloalkyl groups, C1to C6alkoxy groups, C1to C6alkoxycarbonyl groups, a nitro group, and a phenyl group; R is chosen from C1to C6alkyl groups, C1to C6haloalkyl groups, and C3to C6cycloalkyl groups; and n is chosen from integers ranging from 1 to 4, is discussed.
