153123-09-2

Upstream product

• 4206-67-1 iodo(trimethylsilyl)methane 
• 1519-39-7 (R)-methyl p-tolyl sulfoxide 
• 163524-41-2 1-[(4-methylphenyl)sulfanyl]-2-(trimethylsilyl)ethane 

Downstream Products

• 155394-02-8 (2R,3R)-2-<(R)-p-tolylsulfinyl>-1-(trimethylsilyl)-3-octanol 
• 155486-94-5 (2R,3S)-2-<(R)-p-tolylsulfinyl>-1-(trimethylsilyl)-3-octanol 
• 155394-03-9 (2R,3R)-4-methyl-2-<(R)-p-tolylsulfinyl>-1-(trimethylsilyl)-3-pentanol 
• 191422-45-4 (1R,3R)-2,2-Dimethyl-3-[(R)-1-((R)-toluene-4-sulfinyl)-2-trimethylsilanyl-ethyl]-cyclopropanecarboxylic acid ethyl ester 
• 191422-43-2 methyl (R_S,3S,4R)-3-methyl-4-(p-tolylsulfinyl)-5-trimethylsilylpentanoate 
• 191422-44-3 ethyl (R_S,1S,2S)-2-[(1R)-1-(p-tolylsulfinyl)-2-(trimethylsilyl)ethyl]cyclopropanecarboxylate 
• 191422-47-6 ethyl (R_S,1S,2S)-2-[(1R)-1-(p-tolylsulfinyl)-2-(trimethylsilyl)ethyl]cyclohexanecarboxylate 
• 191422-42-1 methyl (R_S,4R)-4-(p-tolylsulfinyl)-5-(trimethylsilyl)pentanoate 
• 264613-49-2 methyl (3R,4R)-3-phenyl-4-[(R)-p-tolylsulfinyl]-5-(trimethylsilyl)pentanoate 

Relevant academic research and scientific papers

Asymmetric chemical oxidations of aryl and alkyl 2-(trimethylsilyl)ethyl sulfides

A collection of aryl and alkyl 2-(trimethylsilyl)methyl sulfides have been converted to their respective sulfoxides by four different asymmetric oxidizing agents. The chemical yields range from 44-98% while the enantiomeric excesses range from 0-89%. The

Vinyl Anion Equivalent V. Asymmetric Synthesis of Allylic Alcohols Using Chiral 2-(Trialkylsilyl)ethyl Sulfoxides

Both enantiomers of optically pure secondary allylic alcohols can be conveniently prepared by the diastereoselective reaction of the α-sulfinyl carbanion of p-tolyl 2-(trialkylsilyl)ethyl sulfoxides or tert-butyl 2-(trimethylsilyl)ethyl sulfoxide with aldehydes followed by either fluoride-induced desilylsulfinylation or thermal elimination of the sulfinyl group.

Convenient Preparation of Optically Pure Propargylic Alcohols Using 2-(Trimethylsilyl)vinyl Sulfoxide As A Novel Chiral Synthon

Both enentiomers of optically pure propargylic alcohols are conveniently prepared by the reaction of α-vinyl anion of 2-(trimethylsilyl)vinyl p-tolyl sulfoxide with aldehydes and subsequent either desilylsulfination or thermal elimination of the sulfinyl group.