191422-45-4Relevant academic research and scientific papers
Efficient synthesis of chrysanthemate precursor from chiral p-tolyl β-(trimethylsilyl)ethyl sulfoxide
Nakamura, Shuichi,Watanabe, Yoshihiko,Toru, Takeshi
, p. 3403 - 3404 (1999)
Reaction of α-lithio-β-silylethyl sulfoxide with ethyl 4-bromo- or 4-chloro-4-methylpent-2-enoate gives the cyclopropanecarboxylate as a single diastereomer which is converted to (1R)-trans-2-formyl-3,3-dimethylcyclopropanecarboxylate in high overall yield. The Royal Society of Chemistry 1999.
Stereoselective conjugate addition of an α-sulfinyl carbanion to α,β-unsaturated esters: Asymmetric synthesis of cycloalkanecarboxylates
Toru, Takeshi,Nakamura, Shuichi,Takemoto, Hirofumi,Ueno, Yoshio
, p. 449 - 450 (2007/10/03)
The reaction of lithiated (R)-2-(trimethylsilyl)ethyl p-tolyl sulfoxide 1 with α,β-unsaturated esters gives 1,4-conjugate addition products as single stereoisomers, whereas the reaction of 1 with 4-, 6-, or 7-haloalkenoates affords cyclopropane-, cyclopen
