153140-16-0

Basic information

• Product Name: 2-Amino-6-(2-carboxyethyl)pyridine
• Synonyms: 2-Amino-6-(2-carboxyethyl)pyridine;6-amino-2-Pyridinepropanoic acid
• CAS NO: 153140-16-0
• Molecular Formula: C8H10N2O2
• Molecular Weight: 166.18
• Product Categories: pharmacetical
• Mol File: 153140-16-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 362.4°Cat760mmHg
• Flash Point: 173°C
• Appearance: /
• Density: 1.289g/cm³
• Vapor Pressure: 6.92E-06mmHg at 25°C
• Refractive Index: 1.603
• PKA: 3.85±0.10(Predicted)
• CAS DataBase Reference: 2-Amino-6-(2-carboxyethyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-6-(2-carboxyethyl)pyridine(153140-16-0)
• EPA Substance Registry System: 2-Amino-6-(2-carboxyethyl)pyridine(153140-16-0)

Safety Data

• Hazardous Substances Data: 153140-16-0(Hazardous Substances Data)

Usage

Structure

Consists of a pyridine ring with an amino group (-NH2) and a carboxyethyl (-CH2COOH) substituent attached at the 6th carbon position.

Derivative

Derived from pyridine.

Potential Pharmaceutical Use

Studied as a building block for the synthesis of various drugs.

Potential Applications

Pharmaceuticals: Utilized as a key component in drug synthesis.
Antioxidant Properties: Investigated for its antioxidant activity.
Antibacterial Properties: Studied for its antibacterial effects.

Medicine and Healthcare

Shows promise for applications in these fields.

Interest for Further Research and Development

Its chemical properties and potential applications make it a compound of interest for further study and potential utilization.

InChI:InChI=1/C8H10N2O2/c9-7-3-1-2-6(10-7)4-5-8(11)12/h1-3H,4-5H2,(H2,9,10)(H,11,12)

Upstream product

• 153140-22-8 2-tritylaminopyridine-6-carbaldehyde 
• 26893-72-1 6-acetamido-picolinic acid 
• 69142-64-9 ethyl 6-aminopicolinate 
• 5327-33-3 2-acetylamino-6-methylpyridine 
• 23628-31-1 6-aminopicolinic acid 
• 1824-81-3 2-Amino-6-methylpyridine 
• 153140-25-1 2-Tritylamino-6-(2-carboxyethyl)pyridine 
• 153140-24-0 Diethyl (6-tritylamino-2-pyridyl)methylmalonate 
• 153140-23-9 Ethyl 2-ethoxycarbonyl-3-(6-tritylamino-2-pyridyl)acrylate 
• 153140-21-7 Ethyl 6-tritylaminopicolinate 

Relevant articles and documents

Method of producing a conjugate utilizing a 2-amino-pyridine compound

2-Aminopyridine derivatives having a bifunctional or unifunctional structure and capable of serving as reactants in synthetically converting organic compounds, such as carbohydrates, proteins, lipids or polymer resins, to desired conjugated structures sui

FUNCTIONAL FLUORESCENCE LABELING OF CARBOHYDRATES AND ITS USE FOR PREPARATION OF NEOGLYCOCONJUGATES

New bifunctional reagents, 2-amino-6-carboxyethylpyridine and 2-amino-6-cyanoethylpyridine, were designed and synthesized in order to provide a novel procedure for preparation of neoglycoconjugates from fluorescence-labeled and purified sugar chains.Labeling of model sugar chains with these reagents was effected by reductive amination using BH3*Me2NH to give corresponding 6-carboxyethylpyridylaminated (CEPA-) and 6-cyanoethylpyridylaminated (CNEPA-) derivatives, which were readily purified by reversed phase HPLC.The reagent parts of the labeled products possess the functional groups which then serve as linkers for coupling with matrices such as proteins and polymers.A CEPA-derivative of glucose was directly coupled with the ε-amino group of a Lys derivative to give a neoglycoprotein model.CNEPA-sugars were hydrogenated to give 6-aminopropylpyridylaminated (APPA-) derivatives, which can then be readily used for the preparation of various types of neoglycoconjugates by use of appropriate spacers as exemplified by the coupling of APPA-maltotriose with bovine serum albumin (BSA), biotin, and acrylic acid.The reaction of APPA-maltotriose with succinimidyl 3-(3-nitro-2-pyridyldithio)propionate gave the corresponding amide to be used for a disulfide formation with BSA.Condensation with biotin was effected by use of N-hydroxysuccinimidobiotin.The conjugation of APPA-maltotriose with acrylic acid was carried out by use of 4-acryloyloxyphenyldimethylsulfonium methylsulfate to give the corresponding acrylamide, which can be used for the preparation of sugar-acrylamide copolymers.