1531634-31-7 Usage
General Description
AF38469 is a potent and selective inhibitor of the Kv1.3 potassium channel, a key regulator of T cell activation and proliferation. It has been shown to effectively suppress the activity of effector memory T cells, which play a critical role in the pathogenesis of autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and type 1 diabetes. AF38469 has shown promising results in preclinical studies as a potential therapeutic agent for the treatment of these autoimmune diseases. Its specificity for Kv1.3 channel inhibition makes it a valuable tool for studying the role of this channel in T cell function and for developing novel treatment strategies for autoimmune disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 1531634-31-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,3,1,6,3 and 4 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1531634-31:
(9*1)+(8*5)+(7*3)+(6*1)+(5*6)+(4*3)+(3*4)+(2*3)+(1*1)=137
137 % 10 = 7
So 1531634-31-7 is a valid CAS Registry Number.
1531634-31-7Relevant articles and documents
N-SUBSTITUTED-5-SUBSTITUTED PHTHALAMIC ACIDS AS SORTILIN INHIBITORS
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Page/Page column 64-65, (2015/02/06)
The present invention is directed to N-substituted-5-substituted phthalamic acids which of formula (A). The compounds are considered useful for the treatment of diseases treatment of a neurodegenerative disease, psychiatric disease, motorneuron disease, peripheral neuropathies, pain, neuroinflammation or atherosclerosis such as Alzheimer's disease and Parkinson's disease.
