153170-76-4Relevant articles and documents
SYNTHESIS OF LY288601, A 5,6-DIHYDROPYRROLOPYRIMIDINE BASED ANTIFOLATE COMPOUND RELATED TO LY231514
Barnett, Charles J.,Wilson Thomas M.
, p. 925 - 936 (2007/10/02)
An expeditious synthesis of LY288601 (2), the 5,6-dihydro analog of the pyrrolopyrimidine-based antifolate compound LY231514 (1a), is described.The synthesis proceeds in eight steps from tert-butyl 4-iodobenzoate and involves the elaboration of a 2