153181-28-3

Basic information

• Product Name: (4R,5S,6S,7R)-4,7-Dibenzyl-1-cyclopropylmethyl-5,6-bis-(2-methoxy-ethoxymethoxy)-[1,3]diazepan-2-one
• CAS NO: 153181-28-3
• Molecular Weight: 556.7
• Mol File: 153181-28-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4R,5S,6S,7R)-4,7-Dibenzyl-1-cyclopropylmethyl-5,6-bis-(2-methoxy-ethoxymethoxy)-[1,3]diazepan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S,6S,7R)-4,7-Dibenzyl-1-cyclopropylmethyl-5,6-bis-(2-methoxy-ethoxymethoxy)-[1,3]diazepan-2-one(153181-28-3)
• EPA Substance Registry System: (4R,5S,6S,7R)-4,7-Dibenzyl-1-cyclopropylmethyl-5,6-bis-(2-methoxy-ethoxymethoxy)-[1,3]diazepan-2-one(153181-28-3)

Safety Data

• Hazardous Substances Data: 153181-28-3(Hazardous Substances Data)

Upstream product

• 7051-34-5 cyclopropylcarbinyl bromide 
• 153181-25-0 (4R,5S,6S,7R)-hexahydro-5,6-bis(2-methoxyethoxymethoxy)-4,7-bis(phenylmethyl)-2H-1,3-diazepin-2-one 

Downstream Products

• 1054620-91-5 3-[(4R,5S,6S,7R)-4,7-Dibenzyl-3-cyclopropylmethyl-5,6-bis-(2-methoxy-ethoxymethoxy)-2-oxo-[1,3]diazepan-1-ylmethyl]-N-(1H-imidazol-2-yl)-benzamide 
• 186040-82-4 3-[(4R,5S,6S,7R)-4,7-Dibenzyl-3-cyclopropylmethyl-5,6-bis-(2-methoxy-ethoxymethoxy)-2-oxo-[1,3]diazepan-1-ylmethyl]-benzoic acid 
• 186040-81-3 3-[(4R,5S,6S,7R)-4,7-Dibenzyl-3-cyclopropylmethyl-5,6-bis-(2-methoxy-ethoxymethoxy)-2-oxo-[1,3]diazepan-1-ylmethyl]-benzonitrile 

Relevant articles and documents

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Cyclic urea amides, a novel series of HIV-1 protease (HIV PR) inhibitors, have increased activity against drug-resistant mutants of the HIV PR. The design strategy for these inhibitors is based on the hypotheses that (i) the hydrogen-bonding interactions