153233-81-9

Basic information

• Product Name: 2-(2-BROMOPHENYL)-4-PHENYL-4,5-DIHYDROOXAZOLE
• Synonyms: 2-(2-BROMOPHENYL)-4-PHENYL-4,5-DIHYDROOXAZOLE
• CAS NO: 153233-81-9
• Molecular Formula: C15H12BrNO
• Molecular Weight: 302.17
• Mol File: 153233-81-9.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 422.2 °C at 760 mmHg
• Flash Point: 209.1 °C
• Appearance: /
• Density: 1.42 g/cm³
• PKA: 3.07±0.70(Predicted)
• CAS DataBase Reference: 2-(2-BROMOPHENYL)-4-PHENYL-4,5-DIHYDROOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-BROMOPHENYL)-4-PHENYL-4,5-DIHYDROOXAZOLE(153233-81-9)
• EPA Substance Registry System: 2-(2-BROMOPHENYL)-4-PHENYL-4,5-DIHYDROOXAZOLE(153233-81-9)

Safety Data

• Hazardous Substances Data: 153233-81-9(Hazardous Substances Data)

Usage

Heterocyclic ring

5-membered dihydrooxazole
A heterocyclic ring is a closed loop of atoms with at least one non-carbon atom, and a 5-membered ring has five atoms in the loop.

Oxygen and nitrogen atoms

Present in the heterocyclic ring
The presence of these atoms contributes to the compound's reactivity and chemical properties.

Bromo group

Attached to the phenyl group
A bromo group is a bromine atom bonded to a carbon atom, which can influence the compound's reactivity and stability.

Phenyl group

Attached to the dihydrooxazole ring
A phenyl group is a benzene ring with one hydrogen atom replaced by a side chain, which can affect the compound's electronic properties.

Functional groups

Bromo and phenyl groups
Functional groups are specific groups of atoms within a molecule that determine its chemical properties and reactivity.

Uses

Building block for pharmaceuticals, agrochemicals, and materials
The compound can be used as an intermediate in the synthesis of various products, making it a versatile building block.

Chemical structure and properties

Valuable and versatile for new chemical applications
The unique structure and properties of the compound make it a promising candidate for the development of new applications in various fields.

Upstream product

• 2042-37-7 o-cyanobromobenzene 
• 20989-17-7 (2S)-2-phenylglycinol 
• 7154-66-7 2-bromobenzoic acid chloride 
• 20989-17-7 Phenylglycinol 
• 88-65-3 2-bromobenzoic-acid 
• 2935-35-5 (S)-2-phenylglycine 
• 56613-80-0 D-2-phenylglycinol 
• 6630-33-7 ortho-bromobenzaldehyde 

Downstream Products

• 189169-55-9 2-[2'-(diphenylphosphanyl)phenyl]-4-phenyl-4,5-dihydrooxazole 
• 2509221-06-9 (S)-4-phenyl-2-(2-((R)-p-tolylsulfinyl)phenyl)-4,5-dihydrooxazole 
• 1609167-92-1 (4R)-4,5-dihydro-2-(2′-anilinophenyl)-4-phenyloxazole 

Relevant articles and documents

Copper(I) Phosphinooxazoline Complexes: Impact of the Ligand Substitution and Steric Demand on the Electrochemical and Photophysical Properties

A series of seven homoleptic CuI complexes based on hetero-bidentate P^N ligands was synthesized and comprehensively characterized. In order to study structure–property relationships, the type, size, number and configuration of substituents at the phosphinooxazoline (phox) ligands were systematically varied. To this end, a combination of X-ray diffraction, NMR spectroscopy, steady-state absorption and emission spectroscopy, time-resolved emission spectroscopy, quenching experiments and cyclic voltammetry was used to assess the photophysical and electrochemical properties. Furthermore, time-dependent density functional theory calculations were applied to also analyze the excited state structures and characteristics. Surprisingly, a strong dependency on the chirality of the respective P^N ligand was found, whereas the specific kind and size of the different substituents has only a minor impact on the properties in solution. Most importantly, all complexes except C3 are photostable in solution and show fully reversible redox processes. Sacrificial reductants were applied to demonstrate a successful electron transfer upon light irradiation. These properties render this class of photosensitizers as potential candidates for solar energy conversion issues.

Synthesis of multisubstituted pyrroles by nickel-catalyzed arylative cyclizations of: N -tosyl alkynamides

The synthesis of multisubstituted pyrroles by the nickel-catalyzed reaction of N-tosyl alkynamides with arylboronic acids is reported. These reactions are triggered by alkyne arylnickelation, followed by cyclization of the resulting alkenylnickel species

Enantioselective Allylic C?H Oxidation of Terminal Olefins to Isochromans by Palladium(II)/Chiral Sulfoxide Catalysis

The enantioselective synthesis of isochroman motifs has been accomplished by palladium(II)-catalyzed allylic C?H oxidation from terminal olefin precursors. Critical to the success of this goal was the development and utilization of a novel chiral aryl sul