153247-93-9 Usage
General Description
1-Acetylindoline-5-carboxylic acid is a chemical compound with the molecular formula C11H9NO3. It is a derivative of indoline and contains a carboxylic acid group and an acetyl group. 1-Acetylindoline-5-carboxylic acid is commonly used in the pharmaceutical industry as a building block for the synthesis of various pharmaceutical drugs. It is also known to exhibit certain biological activities, making it a subject of interest in medicinal chemistry research. Additionally, 1-Acetylindoline-5-carboxylic acid has potential applications in the field of organic synthesis and material science due to its unique chemical structure and properties. Overall, this chemical compound has valuable uses in various industries and research fields.
Check Digit Verification of cas no
The CAS Registry Mumber 153247-93-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,2,4 and 7 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 153247-93:
(8*1)+(7*5)+(6*3)+(5*2)+(4*4)+(3*7)+(2*9)+(1*3)=129
129 % 10 = 9
So 153247-93-9 is a valid CAS Registry Number.
153247-93-9Relevant articles and documents
Ring size changes in the development of class I HDAC inhibitors
Cho, Er-Chieh,Liu, Chi-Yuan,Tang, Di-Wei,Lee, Hsueh-Yun
, p. 1387 - 1401 (2021/07/06)
Five pathways involving different ring structures led to generation of fourteen thienylbenzamides (7–20) which display the structure-activity relationships of class I HDAC inhibitors. All the synthesised compounds inhibit HDAC1 and HDAC2 selectively over other isoforms and many inhibit DLD1 and HCT116 cells more effectively than a parent compound. Compounds 8 and 16 inhibit HCT116 cells by activation of the apoptosis pathway.
A new photolabile linker for the photoactivation of carboxyl groups
Nicolaou,Safina,Winssinger
, p. 900 - 903 (2007/10/03)
A new photolabile linker enabling nucleophilic cleavage of a carboxyl functionality upon irradiation with UV light (>290 nm) was developed. When the photocleavage is carried out in the presence of primary or secondary amines, amides are obtained in high yields and purifies, while the intramolecular version of this reaction leads to heterocycles via a cyclorelease mechanism.
