153276-41-6

Upstream product

• 53815-60-4 1-(2-chloroethoxy)-2-methoxybenzene 
• 150800-64-9 2-methyl-4-chloro-5-[4-(piperazin-1-yl)]pyridazin-3(2H)-one 
• 933-76-6 4,5-dichloro-2-methyl-3(2H)-pyridazinone 
• 117132-45-3 4-<2-(2-methoxyphenoxy)ethyl>piperazine 

Relevant academic research and scientific papers

Novel and highly selective postsynaptic α-adrenoreceptor antagonists: Synthesis and structure-activity relationships of alkane-bridged [4-(phenoxyethyl)-1-piperazinyl]-3(2H)-pyridazinones

The synthesis of selected 4-[4-(phenoxyethyl)-1-piperazinyl]-3(2H)-pyridazinones and alkane-bridged dimers of 4-, 5- and 6-[4-(phenoxyethyl)-1-piperazinyl]-3(2H)-pyridazinones is reported. The blocking activity of these compounds was deterrnined on the pre- and postsynaptic α-adrenoreceptors of isolated rat vas deferens.

New pyridazinones: Synthesis and correlation between structure and α-blocking activity

The synthesis of a series of 5-(4-piperazinyl)-3(2H)-pyridazinone has been reported. The blocking activity of these compounds was determined on the pre- and postsynaptic α-adrenoreceptors of isolated rat vas deferens.