1533409-58-3Relevant academic research and scientific papers
Au(III)-catalyzed regio-and stereoselective tandem synthesis of oxazolo fused naphthyridines and isoquinolines from o-alkynylaldehydes
Jha, Rajeev Ranjan,Danodia, Abhinandan Kumar,Kumar, Sushil,Verma, Akhilesh Kumar
supporting information, p. 610 - 615 (2014/01/23)
An efficient tandem approach for the regio-and stereoselective synthesis of oxazolo-fused naphthyridines 3a-g, 3i-l and isoquinolines 3h, 3m via the reaction of o-alkynylaldehydes 1a-i with chiral amino alcohols 2a-c under mild reaction conditions is described. The stereochemistry and structures of the products were assigned via NOESY and X-ray crystallographic studies.
Stereoselective tandem synthesis of oxazolo-fused pyrroloquinolines from o-alkynylaldehydes via Ag(I)-catalyzed regioselective 5-exo-dig ring closure
Jha, Rajeev Ranjan,Aggarwal, Trapti,Verma, Akhilesh Kumar
, p. 2603 - 2608 (2014/05/06)
A tandem approach for the regio- and stereoselective synthesis of oxazolo-fused pyrroloquinolines 3a-l via the reaction of o-alkynylaldehydes 1a-i with chiral amino alcohols 2a-c under mild reaction conditions is described. The possible participation of the pyridine ring in the regioselective formation of 5-exo-dig cyclized products was supported by the controlled experiments. The structures and stereochemistry of the products were confirmed by NOESY and X-ray crystallographic studies.
