88026-82-8 Usage
Description
(2S)-2-amino-2-phenylethan-1-ol hydrochloride, also known as D-Phenylglycine ethanol, is a chiral chemical compound with the molecular formula C8H12ClNO. It is commonly used in organic synthesis and pharmaceutical research due to its chiral center and the biological activity of its (S)-enantiomer. The hydrochloride salt form enhances its solubility and stability, making it suitable for various applications in the pharmaceutical industry.
Uses
Used in Pharmaceutical Synthesis:
(2S)-2-amino-2-phenylethan-1-ol hydrochloride is used as a key intermediate in the synthesis of various pharmaceuticals, including those targeting neurological and neurodegenerative disorders. Its chiral nature allows for the development of enantioselective drugs with improved efficacy and reduced side effects.
Used as a Chiral Auxiliary:
In the field of asymmetric synthesis, (2S)-2-amino-2-phenylethan-1-ol hydrochloride serves as a chiral auxiliary, aiding in the selective formation of desired enantiomers during chemical reactions. This application is crucial for the production of enantiomerically pure compounds, which is essential for the development of effective and safe medications.
Used in Organic Synthesis:
(2S)-2-amino-2-phenylethan-1-ol hydrochloride is utilized in various organic synthesis processes, contributing to the development of new compounds and materials with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science.
Used in Research and Development:
(2S)-2-amino-2-phenylethan-1-ol hydrochloride is also employed in research and development settings to study its potential applications and to develop new methods for its synthesis and use. This includes investigations into its potential therapeutic effects on neurological and neurodegenerative disorders, as well as its utility in the synthesis of novel compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 88026-82-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,0,2 and 6 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 88026-82:
(7*8)+(6*8)+(5*0)+(4*2)+(3*6)+(2*8)+(1*2)=148
148 % 10 = 8
So 88026-82-8 is a valid CAS Registry Number.
88026-82-8Relevant articles and documents
Intermolecular alkyl radical additions to enantiopure N-tert-butanesulfinyl aldimines
Fernandez-Salas, Jose A.,Maestro, M. Carmen,Rodriguez-Fernandez, M. Mercedes,Garcia-Ruano, Jose L.,Alonso, Ines
supporting information, p. 1658 - 1661 (2013/06/26)
The sulfinyl group in (R)-N-tert-butanesulfinyl aldimines provides efficient control of the stereoselectivity in the intermolecular reactions with alkyl radicals. The methodology is applicable to aryl, heteroaryl, benzyl, and alkynyl imines, even those containing CN, CO2Me, COR, and OH groups. The best results are attained with hindered radicals (tertiary and secondary ones) without C=N bond reduction. This reaction complements the well-established organometallic additions to N-sulfinyl aldimines to obtain enantiomerically pure functionalized α-branched primary amines.
