153413-67-3

Upstream product

• 76054-81-4 3'-O-(4,4'-dimethoxytrityl)thymidine 
• 153413-66-2 O-(5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl) O-(4-nitrophenyl) N,N-diisopropylphosphoramidite 
• 824-78-2 4-nitrophenol sodium salt 
• 153413-65-1 O,O'-bis-(4-nitrophenyl) N,N-diisopropylphosphoramidite 
• 100-02-7 4-nitro-phenol 
• 153454-33-2 O-[5'-O-(4,4-dimethoxytrityl)thymidin-3-yl]-O-[3'-O-(4,4-dimethoxytrityl)thymidin-5'-yl]N,N-diisopropylphosphoramidite 

Downstream Products

• 153413-68-4 C₆₉H₆₇Cl₂N₄O₁₄PS 
• 153413-69-5 S-(2,4-dichlorobenzyl)-5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl 3'-O-(4,4'-dimethoxytrityl)thymidin-5-yl phosphoroselenothioate 
• 153454-34-3 C₆₉H₆₇Cl₂N₄O₁₄PS₂ 

Relevant academic research and scientific papers

New phosphitylating reagent in the nucleotide chemistry containing two 4-nitrophenoxy leaving groups. Remarkably fast and clean phosphitylations activated by DBU leading to thio- and seleno-oligonucleotides

A new synthetic approach to modified oligonucleotides based on N,N′-diisopropyl-di-(4-nitrophenyl)phosphoroamidite 1 is described. The procedure involves displacement of either 4-nitrophenoxy or diisopropylamino ligands. The former proceeds very fast in t