153428-07-0

Upstream product

• 153428-05-8 (S)-2-[(R)-2-(2,2,2-Trichloro-ethoxycarbonylmethyl)-octanoyl]-tetrahydro-pyridazine-1,3-dicarboxylic acid 1-benzyl ester 3-tert-butyl ester 
• 153428-03-6 2,2,2-trichloroethyl 3-(R)-benzyloxycarbonylnonanoate 
• 153428-01-4 tert-butyl 3-(R)-benzyloxycarbonylnonanoate 
• 153428-02-5 (R)-2-Hexyl-succinic acid 1-benzyl ester 
• 163389-03-5 (R)-3-Chlorocarbonyl-nonanoic acid 2,2,2-trichloro-ethyl ester 
• 153427-99-7 (4S)-2,3,4,5-tetrahydro-4-(1-methylethyl)-N-octanoyloxazol-2-one 
• 111-64-8 n-octanoic acid chloride 

Downstream Products

• 163388-97-4 (S)-2-[(R)-2-(Benzyloxycarbamoyl-methyl)-octanoyl]-3-methylcarbamoyl-tetrahydro-pyridazine-1-carboxylic acid benzyl ester 
• 153428-08-1 (S)-2-[(R)-2-(Benzyloxycarbamoyl-methyl)-octanoyl]-tetrahydro-pyridazine-1,3-dicarboxylic acid 1-benzyl ester 

Relevant academic research and scientific papers

Synthesis and structure-activity relationships of gelatinase inhibitors derived from matlystatins

To investigate a series of new inhibitors of gelatinases based on matlystatin B (1b), extensive structure-activity relationship studies were performed. The new derivatives were evaluated in vitro for the ability to inhibit gelatinases. The inhibitory acti