153449-80-0Relevant academic research and scientific papers
Synthesis of 3-nitroindoles by sequential paired electrolysis
Kilmartin, Paul A.,Lindsay, Ashley C.,Sperry, Jonathan
supporting information, p. 7903 - 7913 (2021/09/28)
3-Nitroindoles are synthetically versatile intermediates but current methods for the preparation hinder their widespread application. Herein, we report that nitroenamines undergo electrochemical cyclisation to 3-nitroindoles in the presence of potassium iodide. Detailed control experiments and cyclic voltammogram studies infer the reaction proceedsviaa sequential paired electrolysis process, beginning with anodic oxidation of iodide (I?) to the iodine radical (I˙), which facilitates cyclisation of the nitroenamine to give a 3-nitroindolinyl radical. Cathodic reduction and protonation generates a 3-nitroindoline that upon oxidation forms the 3-nitroindole.
Studies on Formazans: Preparation and Antimicrobial Activity of 2-Phenyl-3-indole
Trivedi, B. H.,Shah, V. H.
, p. 765 - 766 (2007/10/02)
The titled derivatives have been synthesised by the reaction of 2-phenyl-3-aminoindole with different aromatic aldehydes to yield Schiff bases.These Schiff bases are treated with diazotised aromatic amines at lower temperature.The compounds have been screened for antimicrobial activity.
