153465-10-2Relevant academic research and scientific papers
Straightforward preparation of unsymmetrical triorganotin hydrides through new (diorganostannyl) lithiums
Connil, Marie-Fran?oise,Jousseaume, Bernard,Noiret, Nicolas,Pereyre, Michel
, p. 24 - 25 (1994)
Metalation of diorganostannanes R12SnH2 by lithium diisopropylamide afforded the corresponding (diorganostannyl)lithiums, R12SnHLi. Further reaction with halides led to unsymmetrically substituted alk
Novel amino propyl substituted organo tin compounds
Pichler, Johann,Torvisco, Ana,Bottke, Patrick,Wilkening, Martin,Uhlig, Frank
, p. 565 - 573 (2014/06/10)
In this work, a new synthetic pathway yielding unprotected amino propyl tin compounds is described.For this purpose, mono stannanes with different substitution patterns are used.In a first step, tin hydrides are deprotonated using lithium diisopropyl amide and mixed with an electrophile containing a protected amine in the cω;-position.After deprotection via acidic hydrolysis, the desired amino propyl tin compounds are obtained in high yield and purity.The thermal reaction behavior of the amino propyl tin hydrohalide intermediates containing one aromatic residue at the central tin atom is also investigated.For this purpose, amino propyl tin hydrohalides are heated under vacuum until the aromatic hydrocarbon is liberated.This thermal treatment leads to so far unknown tin halides containing an amino propyl side chain.For all of these substances detailed liquid 1H, 13C, and 119Sn-nuclear magnetic resonance (NMR) data were obtained, and in one case solid state NMR is also conducted.Regarding solids, single crystal X-ray analysis is performed.Some derivatization reactions with these new substances are demonstrated, especially the synthesis of an amino propyl tin carboxylate, which might be very interesting for biological, pharmaceutical, or technical processes.
Direct access to unsymmetrical tin hydrides through (hydridodiorganostannio)lithiums
Connil, Marie-Fran?oise,Jousseaume, Bernard,Pereyre, Michel
, p. 4469 - 4472 (2008/10/08)
Metalation of diorganostannanes R12SnH2 by lithium diisopropylamide afforded the corresponding (hydridodiorganostannio)lithiums, R12SnHLi, which were stable at low temperature. Further reaction with alkyl halides led to functional unsymmetrically substituted alkyldiorganostannanes, R12R2SnH. Tin hydrides with an ω-unsaturated substituent were stable at room temperature. With a 4-pentyl chain, they underwent a specific cyclization process, giving a stannacyclohexane under radical reaction conditions. A tin hydride with a tin-silicon bond could also be prepared.
