153617-29-9Relevant academic research and scientific papers
Acyl palladium species in synthesis: Single-step synthesis of α,β-unsaturated ketones from acid chlorides
Cox, Russell J.,Evitt, Andrew S.
, p. 229 - 232 (2007)
Conditions are reported for the facile, one-pot synthesis of α,β-unsaturated ketones via the palladium-catalysed cross-coupling of acyl chlorides with hydrozirconated acetylenes, and its use in the 2-step synthesis of d-5-O-benzyl deoxyxylulose. The Royal Society of Chemistry.
The stereochemical course and mechanism of the IspH reaction
Citron, Christian A.,Brock, Nelson L.,Rabe, Patrick,Dickschat, Jeroen S.
, p. 4053 - 4057 (2012/06/01)
On the right path: The stereochemcial course of the IspH reaction, the last reaction in the deoxyxylulose phosphate pathway to terpenes, was investigated in feeding experiments with deuterated isotopologues of 1-deoxy-D-xylulose. The results support an enzyme mechanism for IspH that involves a previously suggested metallacyclopropane intermediate. Copyright
A short enantioselective synthesis of 1-deoxy-L-xylulose by antibody catalysis
Shabat, Doron,List, Benjamin,Lerner, Richard A.,Barbas III, Carlos F.
, p. 1437 - 1440 (2007/10/03)
A new efficient synthesis of 1-deoxy-L-xylulose (1) is presented. The key step is achieved by a highly enantioselective aldol addition of hydroxyacetone to benzyloxyacetaldehyde via antibody catalysis. The synthesis described here should provide a convenient route to isotopically labeled derivatives.
