15365-59-0Relevant academic research and scientific papers
Syntheses of Isocyanides at the Metal, X. - Radical Alkylation of Cyano Complexes, III. - α-Halogenoalkyl Isocyanides
Fehlhammer, Wolf Peter,Degel, Fritz,Beck, Gerhard
, p. 461 - 470 (2007/10/02)
The α-halogenoalkyl isocyanides CNCH2Cl, CNCHCl2, CNCCl3, 13CNCCl3, CNCFCl2, CNCHClCH2Cl, CNCCl2CH2Cl, CNCCl2CHCl2, CNCH2Br, CNCF2Br, CNCF3, CNnC3F7, and CNnC4F9 are synthesized at the "protective metal" according to (-) + ArN2(+) + RX --> Cr(CO)5CNR + ArX + N2.In general, it is the solvent RX (X = H, Hal) which provides the side chain of the isocyanide.In less reactive and less polar solvents, however, the formation of acyl- and/or aroyl isocyanide complexes becomes prevalent.In the presence of dioxygen, (OC)5CrCNC(=O)NCCr(CO)5 is the main product of the reaction in chloroform.
