153695-19-3

Basic information

• Product Name: 3'-(4-azidobenzamido)taxol
• Synonyms: 3'-(4-azidobenzamido)taxol
• CAS NO: 153695-19-3
• Molecular Formula: C₄₇H₅₀N₄O₁₄
• Molecular Weight: 894.9183
• Mol File: 153695-19-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: 3'-(4-azidobenzamido)taxol(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-(4-azidobenzamido)taxol(153695-19-3)
• EPA Substance Registry System: 3'-(4-azidobenzamido)taxol(153695-19-3)

Safety Data

• Hazardous Substances Data: 153695-19-3(Hazardous Substances Data)

Usage

Chemical Structure

Synthetic derivative of taxol
Azide group linked to the 3'-position of the benzoylphenylisoserine side chain

Purpose

Used in chemotherapy
Employed in targeted drug delivery systems
Utilized in biological studies

Key Features

Contains an azide group
Allows for bioorthogonal labeling
Facilitates conjugation to other molecules

Applications

Medicinal chemistry
Cancer research

Significance

Versatile tool for drug development
Valuable for biological studies
Offers potential therapeutic applications

Upstream product

• 14848-01-2 4-azidobenzoyl chloride 
• 133524-70-6 13-(O-2R-hydroxy-3S-amine-phenylpropionyl)-baccatin III 
• 132127-31-2 (3R,4S)-3-triisopropylsilyloxy-4-phenylazetidin-2-one 
• 53053-08-0 4-azidobenzoic acid N-hydroxysuccinimide ester 
• 160237-83-2 7-(triethylsilyl)baccatin III 13--(2'R,3'S)-3'-phenylisoserinate> 
• 155399-27-2 7-(triethylsilyl)baccatin III 13- 
• 155399-25-0 (3R,4S)-1-(benzyloxycarbonyl)-3-<(tert-butyldimethylsilyl)oxy>-4-phenyl-2-azetidinone 
• 132127-30-1 (3R,4S)-3-<(tert-butyldimethylsilyl)oxy>-4-phenylazetidin-2-one 
• 6427-66-3 4-azidobenzoic acid 
• 326923-31-3 C₆₂H₈₄N₄O₁₄Si₂ 
• 326923-28-8 (3R,4S)-1-(4-Azido-benzoyl)-4-phenyl-3-triisopropylsilanyloxy-azetidin-2-one 

Relevant articles and documents

Characterization of Two Taxol Photoaffinity Analogues Bearing Azide and Benzophenone-Related Photoreactive Substituents in the A-Ring Side Chain

Taxol is a structurally novel and clinically effective antitumor drug, which, unlike other antimitotic agents, induces the assembly of tubulin into microtubules.To characterize the binding site(s) of taxol on the microtubule, taxol-based photoaffinity rea

Direct, efficient and selective tritiations of paclitaxel and photoaffinity taxoids

Radiolabeled paclitaxel and three photophore-bearing derivatives were prepared by organoiridium-mediated direct tritium exchange under both catalytic and stoichiometric conditions. The resulting tritiated taxoids had specific activities ranging from 53 to 195 Ci/mmol. (C) 2000 Elsevier Science Ltd.