15374-15-9 Usage
Description
Dioxopromethazine Hydrochloride is an antihistamine drug that is utilized for the treatment of various conditions, including allergies and symptoms related to the common cold. It functions by blocking the effects of histamine, a substance in the body that can cause allergic symptoms.
Uses
Used in Pharmaceutical Industry:
Dioxopromethazine Hydrochloride is used as an antihistamine for treating [application reason] allergic reactions and symptoms associated with the common cold, such as sneezing, itching, watery eyes, and runny nose. It works by blocking the action of histamine, a compound that causes these symptoms.
Additionally, a scheme was developed that allows the detection of dioxopromethazine in a urine sample within 3 minutes, which can be useful for monitoring drug use in various contexts, such as drug testing or medical diagnostics.
Check Digit Verification of cas no
The CAS Registry Mumber 15374-15-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,3,7 and 4 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 15374-15:
(7*1)+(6*5)+(5*3)+(4*7)+(3*4)+(2*1)+(1*5)=99
99 % 10 = 9
So 15374-15-9 is a valid CAS Registry Number.
InChI:InChI=1/C17H20N2O2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)22(20,21)17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H
15374-15-9Relevant articles and documents
Green technology for preparing dioxopromethazine hydrochloride by using oxygen as oxidant
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Paragraph 0013, (2017/07/21)
The invention discloses a green technology for preparing dioxopromethazine hydrochloride by using oxygen as an oxidant, and belongs to the technical field of medical intermediates. The green technology is characterized in that a target product-the dioxopromethazine hydrochloride can be obtained through a series of reaction by using the oxygen as the oxidant and adopting palladium acetate as a catalyst, and a production process is greatly simplified; compared with a method of using hydrogen peroxide as the oxidant, the yield of an intermediate is much higher, a whole oxidation process requires no addition of sulfuric acid or the hydrogen peroxide, a final product is powder which is white to yellowish or crystalline powder, and the final product is odorless and is bitter in taste and very high in purity. By adopting an improved synthesis path, the green technology disclosed by the invention has multiple advantages that the yield is increased to a large extent, the cost is reduced, safety is increased, energy is saved, and the like, and modern chemical industry production requirements of green reaction are met.
