153751-71-4Relevant academic research and scientific papers
Synthesis of 7a-substituted Hajos-Wiechert ketone analogues
Kennedy, Jason W. J.,Vietrich, Sophia,Weinmann, Hilmar,Brittain, Dominic E. A.
, p. 5151 - 5154 (2008/09/21)
(Chemical Equation Presented) A general and efficient route to 2-substituted 1,3-cyclopentadiones 3 has been developed. This operationally simple, two-step procedure is amenable to multigram scale preparations of these useful synthetic intermediates. These compounds are then transformed to previously unknown, higher analogues of the Hajos-Parrish-Eder-Sauer-Wiechert ketone (enone 1, R = Me) following an enantioselective Robinson annulation.
