1538-98-3

Basic information

• Product Name: p-Tolylsulfonyldiazomethane
• Synonyms: p-Tolylsulfonyldiazomethane;Diazomethyl p-tolyl sulfone
• CAS NO: 1538-98-3
• Molecular Formula: C₈H₈N₂O₂S
• Molecular Weight: 196.22632
• Mol File: 1538-98-3.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: p-Tolylsulfonyldiazomethane(CAS DataBase Reference)
• NIST Chemistry Reference: p-Tolylsulfonyldiazomethane(1538-98-3)
• EPA Substance Registry System: p-Tolylsulfonyldiazomethane(1538-98-3)

Safety Data

• Hazardous Substances Data: 1538-98-3(Hazardous Substances Data)

Upstream product

• 3937-96-0 tosylacetic acid 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 2850-26-2 (toluene-4-sulfonylmethyl)-carbamic acid ethyl ester 
• 6462-07-3 p-Toluolsulfonyl-acetaldehyd-enolacetat 
• 6739-66-8 (toluene-4-sulfony)acetaldehyde 
• 2951-53-3 N-nitroso-(toluene-4-sulfonylmethyl)-carbamic acid ethyl ester 
• 2725-60-2 1-(p-methylphenylsulfonyl)-1-diazopropan-2-one 

Downstream Products

• 34006-56-9 α-(5-Chlorpentoxy)-α-chlormethyl-p-tolylsulfon 
• 34006-58-1 α-(2-Methoxyaethoxy)-α-chlormethyl-p-tolylsulfon 
• 32641-87-5 α-Aethoxy-α-chlormethyl-p-tolylsulfon 
• 14894-58-7 p-tolylsulfonylmethyl p-toluenesulfonate 
• 107696-99-1 trans-2,2-dimethyl-3-(p-tolylsulfonyl)cyclopropyl methyl ether 
• 107696-99-1 cis-2,2-dimethyl-3-(p-tolylsulfonyl)cyclopropyl methyl ether 
• 122016-58-4 1-Methyl-4-(1-vinyl-octyloxymethanesulfonyl)-benzene 
• 345928-65-6 1-(2-Methoxy-2-phenyl-cyclopropanesulfonyl)-4-methyl-benzene 
• 141241-08-9 3-Phenyl-1-(toluene-4-sulfonyl)-butan-2-one 
• 101268-22-8 3,3-dimethyl-1-(p-tolylsulfonyl)butan-2-one 
• 61286-74-6 p-Toluolsulfonyldideuteromethylnitrat 
• 34292-15-4 p-Toluolsulfonylmethylnitrat 
• 122410-17-7 C₂₀H₂₄O₄S 
• 62586-48-5 p-Tolylsulfonylmethyl-methansulfonate 

Relevant articles and documents

From Rare Reagents to Rare Products: Regiospecific Silver-Catalyzed [3+2] Cycloaddition of Aryl-, Alkyl- and Aminosulfonyl Diazomethanes with Arenediazonium Tosylates

The scope of silver nitrate-catalyzed cycloaddition of arenediazonium salts has been expanded to include aryl- and alkylsulfonyl diazomethanes as well as the recently introduced diazomethyl sulfonamides. The reliance on these two classes of diazo compounds led to a new synthetic approach to the rare 2-aryltetrazol-5-yl sulfones as well as to the synthesis of hitherto not described 2-aryltetrazol-5-yl sulfonamides.

Synthesis of Sulfonyldiazomethanes and Acetyldiazomethanes via an Alumina-Mediated Decarboxylation Strategy

Diazo compounds are widely adopted in organic synthesis due to their carbine characteristics. One of the most interesting diazo compounds is diazolsulfonyl. Here, in the current study, we found that diazolsufonyl compounds could be prepared with moderate

Cobalt-catalyzed asymmetric cyclopropanation with diazosulfones: Rigidification and polarization of ligand chiral environment via hydrogen bonding and cyclization

A new D2-symmetric chiral porphyrin P6 (2,6-DiMeO-ZhuPhyrin) with enhanced chiral rigidity and polarity was designed and synthesized through incorporation of hydrogen bonding and cyclic structure. Its cobalt(II) complex [Co(P6)] is a highly active and selective catalyst for asymmetric cyclopropanation of alkenes with diazosulfones. The [Co(P6)]-based catalytic system is suitable for various aromatic olefins as well as electron-deficient olefins, including α,β-unsaturated esters, ketones, and nitriles, forming the corresponding cyclopropyl sulfones under mild conditions in high yields and high selectivities. In most cases, both excellent diastereo- and enantioselectivities were achieved. Copyright