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Usage

Uses

Used in Chemical Synthesis:
4-OXO-4-([3-(TRIFLUOROMETHYL)PHENYL]AMINO)BUTANOIC ACID is used as a building block in chemical synthesis for creating more complex organic molecules. Its unique structure allows for versatile reactions and the formation of a wide range of compounds.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 4-OXO-4-([3-(TRIFLUOROMETHYL)PHENYL]AMINO)BUTANOIC ACID is used as a potential candidate in drug discovery and development. Its specific properties may contribute to the creation of new therapeutic agents, particularly in the context of medicinal chemistry where novel compounds are constantly being explored for their biological activity and potential health benefits.
Used in Drug Design:
4-OXO-4-([3-(TRIFLUOROMETHYL)PHENYL]AMINO)BUTANOIC ACID is utilized in drug design for its potential to be incorporated into new pharmaceutical compounds. Its structural features may offer advantages in terms of drug efficacy, selectivity, and pharmacokinetics, which are critical factors in the development of effective medications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 4-OXO-4-([3-(TRIFLUOROMETHYL)PHENYL]AMINO)BUTANOIC ACID is used as a subject of research to understand its interactions with biological targets and its potential therapeutic effects. This research can lead to insights that inform the design of new drugs with improved properties and applications in medicine.

InChI:InChI=1/C11H10F3NO3/c12-11(13,14)7-2-1-3-8(6-7)15-9(16)4-5-10(17)18/h1-3,6H,4-5H2,(H,15,16)(H,17,18)

Upstream product

• 108-30-5 succinic acid anhydride 
• 98-16-8 3-trifluoromethylaniline 

Downstream Products

• 23115-75-5 (C₄H₉)3SnOOCCH₂CH₂CONHC₆H₄CF₃ 

Relevant academic research and scientific papers

Synthesis, characterization, and biological activity of organotin(IV) complexes with 4-oxo-4-[3-(trifluoromethyl)phenylamino]butanoic acid

Metal complexes display functional interfaces for association with and stimulation of certain enzymes, that are liable to transfer genetic information in DNA for synthesis of specific proteins. Biological activity of five organotin carboxylates based on the ligand, 4-oxo-4-[3-(trifluoromethyl)phenylamino]butanoic acid, such as [Bu3SnL] (1), [Ph3SnL] (2), [Me2SnL2] (3), [Bu2SnL2] (4), and [Ph2SnL2] (5) have been synthesized and their biological activity as a function of substitution on the ligand was tested. Structure of the complexes was evaluated by elemental analysis, FT-IR and 1H, and 13C NMR spectra. FT-IR data and theoretical calculations revieled that the ligand acted as bidentate in complexes 1–5. NMR data revealed four and six coordinated geometry of tin in solutions. The HOMO–LUMO study indicated thermodynamic stability of the complexes. AFM confirmed catalytic potential of the synthesized complexes. Biological screening showed that, with few exceptions, all the complexes exhibited significant activity against various bacterial and fungal strains. UV-Vis study confirmed that the ligand and its complexes binded to DNA via intercalative interactions.

Design, synthesis and biological evaluation of anilide (dicarboxylic acid) shikonin esters as antitumor agents through targeting PI3K/Akt/mTOR signaling pathway

Triple-negative breast cancer (TNBC) has an unfavorable prognosis attribute to its low differentiation, rapid proliferation and high distant metastasis rate. PI3K/Akt/mTOR as an intracellular signaling pathway plays a key role in the cell proliferation, m