153946-95-3

Upstream product

• 114092-19-2 (2S,4R)-6-heptene-1,2,4-triol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 478491-15-5 (3S)-4-(tert-butyldiphenylsilanyloxy)-hydroxy-N-methoxy-N-methylbutyramide 
• 124655-05-6 (S)-methyl 4-(tert-butyldiphenylsilyloxy)-3-hydroxybutanoate 
• 87318-96-5 (4S)-4-((2R)-2-hydroxypent-4-enyl)-2,2-dimethyl-1,3-dioxolane 

Downstream Products

• 153946-96-4 ((4S,6R)-6-Allyl-2,2-dimethyl-[1,3]dioxan-4-ylmethoxy)-tert-butyl-diphenyl-silane 
• 205372-02-7 2,2-Dimethyl-propionic acid (2S,4R)-4-benzyloxy-2-(tert-butyl-dimethyl-silanyloxy)-hept-6-enyl ester 
• 1028224-73-8 2,2-Dimethyl-propionic acid (2S,4R)-4-benzyloxy-2-hydroxy-hept-6-enyl ester 
• 205372-00-5 ((4S,6R)-6-Allyl-2-phenyl-[1,3]dioxan-4-yl)-methanol 
• 205372-01-6 (2S,4R)-4-Benzyloxy-hept-6-ene-1,2-diol 

Relevant academic research and scientific papers

Studies on the stereochemistry of theonezolides A-C1: Elucidation of the relative configurations of 1,3-diol moieties of the C-4 ～ C-17 fragment

Four model compounds having syn and anti 1,3-diol type moieties corresponding to C-8/C-10 and C-14/C-16 positions contained in the C-4 ～ C-17 fragment of theonezolides A-C were prepared. Comparison of their spectral data suggested that the 1,3-diol at C-8/C-10 and the OH/OMe groups at C-14/C-16 positions of theonezolides A-C were both syn.

A synthesis of a C1-C7 building block for the enantiomer of hennoxazole A utilizing a regioselective ring opening of a cyclic acetal

AC1-C7 building block (4) for the enantiomer of hennoxazole A(1), an antivirus and analgesic active marine natural product, was efficiently synthesized from (S)-malic acid utilizing the following key steps: (1) the stereoselective co