15395-61-6Relevant articles and documents
Synthesis and characterization of FeIII(μ-OH)ZnII complexes: Effects of a second coordination sphere and increase in the chelate ring size on the hydrolysis of a phosphate diester and DNA
Silva, Graciela Aparecida Dos Santos,Amorim, André Luiz,Souza, Bernardo De,Gabriel, Philipe,Terenzi, Hernán,Nordlander, Ebbe,Neves, Ademir,Peralta, Rosely A.
, p. 11380 - 11394 (2017)
The synthesis and characterization of three ligands and their respective heterobinuclear FeIIIZnII complexes were carried out, with the goal of mimicking the active site of purple acid phosphatases (PAPs). The ligand 2-hydroxy-3-(((2-hydroxy-5-methyl-3-(((2-(pyridin-2-yl)ethyl)(pyridin-2-ylmethyl)amino)methyl)benzyl)(pyridin-2ylmethyl)amino)methyl)-5-methylbenzaldehyde (H2L2) was synthesized and its complex (FeIIIZnIIL2) was used as a basis for comparison with similar complexes previously published in the literature. Subsequent modifications were conducted in the aldehyde group, where 1,2-ethanediamine and 1,4-diaminobutane were used as side chain derivatives. The compounds FeIIIZnIIL2 (1), FeIIIZnIIL2-et (2) and FeIIIZnIIL2-but (3) were characterized by spectroscopic methods (infrared and UV-Vis) and ESI-MS spectrometry. Theoretical calculations were performed to provide insights into the complex structures with FeIIIZnII structures. The hydrolytic activity was analyzed both with the model substrate 2,4-BDNPP and with DNA catalyzed by complexes 1, 2 and 3.
Erratum: Cu-Catalyzed Three-Component Carboamination of Alkenes (J. Am. Chem. Soc. (2018) 140:1 (58?61) DOI: 10.1021/jacs.7b10529)
Gockel, Samuel N.,Buchanan, Travis L.,Hull, Kami L.
, p. 6019 - 6020 (2021)
Pages 59 and 60. We have identified an error in the structural analysis of compounds presented in our publication detailing. (Table presented).
Reduction of copper(II) complexes of tridentate ligands by nitric oxide and fluorescent detection of NO in methanol and water media
Kumar, Pankaj,Kalita, Apurba,Mondal, Biplab
, p. 8656 - 8663 (2011)
Two copper complexes, 1 and 2, with tridentate N-donor ligands, L 1 and L2 [L1= (1-methyl-1H-imidazol-2-ylmethyl) -(2-pyridin-2-yl-ethyl)amine, L2 = (2-pyridin-2-yl-ethyl)-pyridin-2 yl-methylamine] respectively, have been synthesized and characterized. On exposure to nitric oxide, the copper(ii) centers in complexes 1 and 2 were found to undergo reduction in various solvents. In acetonitrile solvent the reduction was accompanied by a simultaneous N-nitrosation on the secondary amine center on the ligand frameworks. Complexes 3 and 4 were prepared with ligands L 3 and L4, respectively. L3 and L4 [L3 = 5-dimethylamino-naphthalene-1-sulfonic acid (1-methyl-1H-imidazol-2-ylmethyl)-(2-pyridin-2-yl-ethyl)-amide; L4 = 5-dimethylamino-naphthalene-1-sulfonic acid(2-pyridin-2-yl-ethyl)-pyridin-2- ylmethyl-amide] are the dansyl derivatives of L1 and L2, respectively. Complex 4, due to paramagnetic quenching, does not display any fluorescence; however, on addition of nitric oxide to a methanol or water solution of complex 4, the fluorescence intensity of the fluorophore has been found to be restored. This is attributed to the reduction of the Cu(ii) center by nitric oxide to diamagnetic Cu(i). The turn-on of quenched fluorescence intensity has been observed both in methanol and water media. The Royal Society of Chemistry 2011.
DNA binding, nuclease activity and cytotoxicity studies of Cu(ii) complexes of tridentate ligands
Kumar, Pankaj,Gorai, Sukhamoy,Kumar Santra, Manas,Mondal, Biplab,Manna, Debasis
, p. 7573 - 7581 (2012)
Cu(ii) complexes of three tridentate ligands, L1, L2 and L3, [L1, N-((1H-imidazole-2-yl)methyl)-2-(pyridine-2- yl)ethanamine; L2, N-((1-methyl-1H-imidazole-2-yl)methyl)-2- (pyridine-2-yl)ethanamine; L
Preparation of the Ru3(CO)8-pyridine-alcohol cluster and its use for the selective catalytic transformation of primary to secondary amines
Singh, Ajeet,Mobin, Shaikh M.,Mathur, Pradeep
, p. 14033 - 14040 (2018/11/23)
The synthesis of pyridine alcohol based ruthenium carbonyl clusters Ru3(hep)2(CO)8 (1), Ru3(hpp)2(CO)8 (2), and Ru3(bhmp-H)2(CO)8 (3) {hep-H = 2-(2-hydroxyethyl)pyridine, hpp-H = 2-(3-hydroxypropyl)pyridine and bhmp-H2 = 2,6-bis(hydroxymethyl)pyridine} has been carried out by the reaction of the corresponding pyridine-alcohol ligands with Ru3(CO)12. Clusters 1-3 have been characterized using elemental analysis, NMR, FT-IR, mass spectrometry and single-crystal X-ray structures. The clusters were explored for the selective catalytic transformation of primary amines into secondary amines using alcohols as the mono-alkylating agents via hydrogen transfer reactions. All three display efficient catalytic activity with 1 being the most effective.
Cu-Catalyzed Three-Component Carboamination of Alkenes
Gockel, Samuel N.,Buchanan, Travis L.,Hull, Kami L.
supporting information, p. 58 - 61 (2018/01/17)
Copper-catalyzed intermolecular carboamination of alkenes with α-halocarbonyls and amines is presented with 42 examples. Electron rich, electron poor, and internal styrenes, as well as α-olefins, are functionalized with α-halocarbonyls and aryl or aliphat
NEW GADOLINIUM-BASED CONTRAST AGENTS FOR SENSITIVE DETECTION OF ZN2+ WITH MRI
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Page/Page column 38, (2015/11/10)
In some aspects, the present disclosure provides novel ligands, which may be used to make novel MRI contrast agents for the detection of zinc. In further aspects, by the present disclosure also provides methods of using as imaging agents and compositions thereof.
Modification and optimization of the bis-picolylamide-based relay protection for carboxylic acids to be cleaved by unusual complexation with Cu2+ salts
Mundinger, Stephan,Jakob, Uwe,Bichovski, Plamen,Bannwarth, Willi
, p. 8968 - 8979,12 (2012/12/11)
A simple modification of our recently published protection scheme for carboxylic acids as amides resulted in a new protecting group with significantly improved properties. It requires shorter reaction times for deprotection and allows us to replace Cu(OTf)2 by CuCl2, indicating at the same time the importance of the nature of the anion of the Cu2+ source. Since the new scheme fulfills all criteria required for an ideal protection group it should find widespread application in synthetic organic chemistry.
Synthesis and characterization of a new asymmetric dinucleating ligand and its dinuclear nickel(II) complex with (μ-n2)2 phosphate ester bridge
Ren, Yan-Wei,Wu, Ai-Zhi,Liu, Hai-Yang,Jiang, Huang-Feng
experimental part, p. 191 - 195 (2011/10/13)
A new asymmetric phenol-based "end-off" dinucleating ligand HL was prepared using a modified methodology through a four-step synthesis. The ligand comprises two different coordination moieties, namely, a rigid 1,4-dimethyl-1,4,7-triazacyclononane unit and
SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS
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Page/Page column 99; 117, (2009/12/05)
This invention relates to a new sordarin derivative or a pharmaceutically acceptable salt thereof, which has antimicrobial activities (especially, antifungal activities), to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases in a human being or an animal.
