154044-74-3 Usage
Chemical Properties
White Solid
Uses
Different sources of media describe the Uses of 154044-74-3 differently. You can refer to the following data:
1. A intermediate in the synthesis of a metabolite of Docetaxel, an antineoplastic.
2. An intermediate in partial synthesis of major human metabolites of Docetaxel (D494420), an antineoplastic.
Check Digit Verification of cas no
The CAS Registry Mumber 154044-74-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,0,4 and 4 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 154044-74:
(8*1)+(7*5)+(6*4)+(5*0)+(4*4)+(3*4)+(2*7)+(1*4)=113
113 % 10 = 3
So 154044-74-3 is a valid CAS Registry Number.
154044-74-3Relevant articles and documents
Partial synthesis of major human metabolites of docetaxel
Commercon, Alain,Bourzat, Jean-Dominique,Bezard, Daniel,Vuilhorgne, Marc
, p. 10289 - 10298 (2007/10/02)
The structures and synthesis of the four major human metabolites of docetaxel are reported. These metabolites, i.e. compounds 3, 4a,b and 5, are side-chain oxidation derivatives. They were prepared by partial synthesis from the previously described amino-taxoid 8 using mixed-carbonates as acylation reagents. In vitro biological activities are detailed.