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154044-74-3

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  • N-Des-t-boc-N-2-[2-methyl-1-(4-methoxyphenyl)methoxy]propyloxycarbonxyl-7,10-O-bis{[(2,2,2-trichloroethyl)oxy]carbonyl} Docetaxel

    Cas No: 154044-74-3

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  • N-Des-t-boc-N-2-[2-methyl-1-(4-methoxyphenyl)methoxy]propyloxycarbonxyl-7,10-O-bis{[(2,2,2-trichloroethyl)oxy]carbonyl} Docetaxel

    Cas No: 154044-74-3

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154044-74-3 Usage

Chemical Properties

White Solid

Uses

Different sources of media describe the Uses of 154044-74-3 differently. You can refer to the following data:
1. A intermediate in the synthesis of a metabolite of Docetaxel, an antineoplastic.
2. An intermediate in partial synthesis of major human metabolites of Docetaxel (D494420), an antineoplastic.

Check Digit Verification of cas no

The CAS Registry Mumber 154044-74-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,0,4 and 4 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 154044-74:
(8*1)+(7*5)+(6*4)+(5*0)+(4*4)+(3*4)+(2*7)+(1*4)=113
113 % 10 = 3
So 154044-74-3 is a valid CAS Registry Number.

154044-74-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name N-de-t-butoxycarbonyl-N-2-<2-methyl-1-(4-methoxyphenyl)methoxy>propyloxycarbonyl-7,10-O-diTroc-docetaxel

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:154044-74-3 SDS

154044-74-3Relevant articles and documents

Partial synthesis of major human metabolites of docetaxel

Commercon, Alain,Bourzat, Jean-Dominique,Bezard, Daniel,Vuilhorgne, Marc

, p. 10289 - 10298 (2007/10/02)

The structures and synthesis of the four major human metabolites of docetaxel are reported. These metabolites, i.e. compounds 3, 4a,b and 5, are side-chain oxidation derivatives. They were prepared by partial synthesis from the previously described amino-taxoid 8 using mixed-carbonates as acylation reagents. In vitro biological activities are detailed.

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