154057-83-7

Basic information

• Product Name: 4-(4-bromo-phenylsulfanyl)-pyridine
• Synonyms: 4-(4-bromo-phenylsulfanyl)-pyridine
• CAS NO: 154057-83-7
• Molecular Weight: 266.161
• Mol File: 154057-83-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-(4-bromo-phenylsulfanyl)-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-bromo-phenylsulfanyl)-pyridine(154057-83-7)
• EPA Substance Registry System: 4-(4-bromo-phenylsulfanyl)-pyridine(154057-83-7)

Safety Data

• Hazardous Substances Data: 154057-83-7(Hazardous Substances Data)

Upstream product

• 7379-35-3 4-chlorpyridine hydrochloride 
• 106-53-6 para-bromobenzenethiol 
• 934965-59-0 4-iodopyridin-3-yl 4-chlorobenzenesulfonate 
• 188057-20-7 3-hydroxy-4-iodopyridine 

Relevant articles and documents

Preparation of functionalized 3,4-pyridynes via 2-magnesiated diaryl sulfonates

The preparation of functionalized 3,4-pyridynes of type 1 as highly reactive intermediates has been achieved by the controlled elimination of readily generated 2-magnesiated diaryl sulfonates of type 2 obtained by a low temperature I/Mg- or Br/Mg-exchange starting from the corresponding halides of type 3. After trapping with furan, moderate to good yields of the desired functionalized cycloadducts of type 4 are obtained. The addition of a magnesium arylthiolate or magnesium phenylselenide to 3,4-pyridyne followed by quenching with an electrophile is also described.

Therapeutic alcohols

Compounds of formula I STR1 wherein X, A, B, R1 and R2 have the meanings given in the specification, and pharmaceutically acceptable salts and pharmaceutically acceptable in vivo hydrolysable ester thereof, processes for preparing the compounds and pharmaceutical compositions comprising them. The compounds are useful as potassium channel openers and as therapeutic agents in the treatment of urinary incontinence.