154059-97-9Relevant academic research and scientific papers
Nitrosations with hydrazine derivative, VI: Novel reaction of oral antidiabetics of the sulfonylsemicarbazide type under nitrosating conditions
Hanefeld,Hartmann
, p. 925 - 927 (1993)
Oral antidiabetics of the sulfonylsemicarbazide type like Tolazamide (1) and Glisoxepide (2) were transformed under mild nitrosating conditions, even nearly physiological in vitro conditions, to sulfonyl triazenes 3a, b by a novel reaction pathway. Model compounds with N4-Acyl-semicarbazide structure 4 showed different reaction behaviour yielding carbonamides 5 and nitrosamines 6.
