154121-06-9Relevant articles and documents
SYNTHESIS AND PROPERTIES OF 5-FLUORO-6-ALKOXY URACIL DERIVATIVES; FORMATION OF A HIGH AMOUNT OF 'ANTI-GAUCHE'PRODUCTS.
Visser, Gerard W. M.,Wedzinga, R.,Herscheid, J. D. M.
, p. 190 (1991)
-
Photochemical reactions of 5-fluoropyrimidine bases with alcohols
Urjasz, Wojciech,Maciejewski, Andrzej,Celewicz, Lech
, p. 3243 - 3246 (2007/10/03)
Photochemical reactions of 5-fluorocytosine with primary alcohols led to 5-alkoxycytosines and 6-alkoxycytosines as the main photoproducts. These products are formed via reactive intermediates 6-alkoxy-5-fluoro-5,6- dihydrocytosines, whereas photochemical reactions of 5-fluorouracil with alcohols led to stable 6-alkoxy-5-fluoro-5,6-dihydrouracils.
Process for preparation of 6-substituted 5-fluorouracil derivatives
-
, (2008/06/13)
The reaction of certain fluorinated pyrimidine derivatives with hydrogen donor compounds to produce 6-substituted 5-fluoropyrimidines is disclosed. The products so produced are useful in germicidal and antineoplastic applications, and can be converted into 5-fluorouracil, which has known utility in cancer chemotherapy.