15416-91-8

Usage

Uses

1. Used in Pharmaceutical Industry:
Farnesyl monophosphate is used as a key intermediate in the synthesis of various pharmaceutical compounds, particularly those targeting cancer cells. Its unique structure allows for the development of drugs that can modulate cellular signaling pathways, potentially leading to the inhibition of tumor growth and progression.
2. Used in Flavor and Fragrance Industry:
Farnesyl monophosphate is used as a building block for the production of various fragrances and flavors. Its distinct chemical properties enable the creation of a wide range of scents and tastes, making it a valuable component in the development of new and innovative products.
3. Used in Cosmetic Industry:
Farnesyl monophosphate is utilized in the formulation of cosmetics due to its potential benefits for skin health. It may be incorporated into anti-aging products, as it could help promote cell regeneration and improve skin elasticity.
4. Used in Research and Development:
Farnesyl monophosphate serves as an important compound for scientific research, particularly in the fields of biochemistry and molecular biology. It is used to study the mechanisms of various cellular processes and to develop new therapeutic strategies for a range of diseases.

InChI:InChI=1/C15H27O4P/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-19-20(16,17)18/h7,9,11H,5-6,8,10,12H2,1-4H3,(H2,16,17,18)/b14-9-,15-11-

Upstream product

• 4602-84-0 farnesol 
• 106-28-5 Farnesol 

Downstream Products

• 372-97-4 farnesyl pyrophosphate 

Relevant academic research and scientific papers

Enzymatic synthesis of lipid II and analogues

The emergence of antibiotic resistance has prompted active research in the development of antibiotics with new modes of action. Among all essential bacterial proteins, transglycosylase polymerizes lipid II into peptidoglycan and is one of the most favorable targets because of its vital role in peptidoglycan synthesis. Described in this study is a practical enzymatic method for the synthesis of lipid II, coupled with cofactor regeneration, to give the product in a 50-70 % yield. This development depends on two key steps: the overexpression of MraY for the synthesis of lipid I and the use of undecaprenol kinase for the preparation of polyprenol phosphates. This method was further applied to the synthesis of lipid II analogues. It was found that MraY and undecaprenol kinase can accept a wide range of lipids containing various lengths and configurations. The activity of lipid II analogues for bacterial transglycolase was also evaluated.

Probing the Substrate Promiscuity of Isopentenyl Phosphate Kinase as a Platform for Hemiterpene Analogue Production

Isoprenoids are a large class of natural products with wide-ranging applications. Synthetic biology approaches to the manufacture of isoprenoids and their new-to-nature derivatives are limited due to the provision in nature of just two hemiterpene buildin

One-pot synthesis of organophosphate monoesters from alcohols

A one-pot procedure for the phosphorylation of alcohols provides the corresponding phosphate monoesters in improved yields. The protocol features the use of tetrabutylammonium hydrogen phosphate and trichloroacetonitrile, followed by purification of the crude product by flash chromatography on silica gel. The final step, cation exchange chromatography, affords the organophosphates as ammonium salts that are usually required for biochemical applications. The mechanism appears to be phosphate rather than alcohol activation by trichloroacetonitrile.