154170-47-5

Upstream product

• 7564-64-9 3-methyl-1,3,5-pentanetriol 
• 154066-61-2 1,3-O,O-isopropylidene-3-methylpentane-1,3,5-triol 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 
• 148254-22-2 4-[2-phenyl-(1,3-dioxolan-4-yl)]-butan-1-ol 
• 154066-62-3 4-(2-Benzyloxy-ethyl)-2,2,4-trimethyl-[1,3]dioxane 

Downstream Products

• 101268-70-6 (RS)-5-benzyloxy-3-hydroxy-3-methylpentanoic acid 
• 87137-49-3 methyl (RS)-5-benzyloxy-3-hydroxy-3-methylpentanoate 

Relevant academic research and scientific papers

Selective cleavage of acetals with ZnBr2 in dichloromethane

A selective cleavage of acetals of 1,2- and 1,3-diols has been achieved under mild conditions using ZnBr2 in dichloromethane at room temperature. Acetal types cleavable by this procedure include benzylidene, isopropylidene and cyclohexylidene acetals. This method is compatible with several other types of hydroxyl protecting groups such as Bn, Bz, TBDPS, TIPS and TBDMS.

Chirality of the 3-hydroxy-3-methylglutaric acid moiety of fasciculic acid A, a calmodulin antagonist isolated from Naematoloma fasciculare

The chirality of the 3-hydroxy-3-methylglutaric acid (HMGA) moiety of fasciculic acid A (1), a calmodulin antagonist isolated from Naematoloma fasciculare, was established to be S by comparing the 1H-NMR spectrum of the L-alanylamide of HMGA de