154179-39-2

Basic information

• Product Name: 6-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride
• Synonyms: 6-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride;3-[(7-Chloroquinolin-4-yl)amino]phenol hydrochloride;6-[cis-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride
• CAS NO: 154179-39-2
• Molecular Formula: C₁₅H₁₁ClN₂O*ClH
• Molecular Weight: 280
• Mol File: 154179-39-2.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride(154179-39-2)
• EPA Substance Registry System: 6-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride(154179-39-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 154179-39-2(Hazardous Substances Data)

Usage

Description

6-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride is a chemical compound featuring a pyridin-3-amine core with a dimethylmorpholin-4-yl substituent. It is presented as a dihydrochloride salt and is a small molecule with potential applications in pharmaceutical research and development.

Uses

Used in Pharmaceutical Research and Development:
6-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride is used as a potential drug candidate for targeting specific biological pathways or interactions within the body. Its unique structure and properties make it a promising candidate for further research and testing to understand its full potential in various fields.
Used in Drug Development:
In the pharmaceutical industry, 6-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride is utilized as a compound for the development of new drugs. Its specific structure may allow it to interact with biological targets, offering a foundation for creating medications that could address unmet medical needs.
Further research and testing are required to explore the compound's potential applications and to determine its efficacy and safety in various therapeutic areas.

Upstream product

• 86-98-6 4,7-dichloroquinoline 
• 591-27-5 m-Hydroxyaniline 

Relevant articles and documents

Antimycobacterial and photosynthetic electron transport inhibiting activity of ring-substituted 4-arylamino-7-chloroquinolinium chlorides

In this study, a series of twenty-five ring-substituted 4-arylamino-7-chloroquinolinium chlorides were prepared and characterized. The compounds were tested for their activity related to inhibition of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts and also primary in vitro screening of the synthesized compounds was performed against mycobacterial species. 4-[(2-Bromophenyl)amino]-7-chloroquinolinium chloride showed high biological activity against M. marinum, M. kansasii, M. smegmatis and 7-chloro-4-[(2-methylphenyl)amino]quinolinium chloride demonstrated noteworthy biological activity against M. smegmatis and M. avium subsp. paratuberculosis. The most effective compounds demonstrated quite low toxicity (LD50 > 20 μmol/L) against the human monocytic leukemia THP-1 cell line within preliminary in vitro cytotoxicity screening. The tested compounds were found to inhibit PET in photosystem II. The PETinhibiting activity expressed by IC50 value of the most active compound 7-chloro-4-[(3-trifluoromethylphenyl)amino]quinolinium chloride was 27 μmol/L and PET-inhibiting activity of ortho-substituted compounds was significantly lower than this of meta- and para-substituted ones. The structure-activity relationships are discussed for all compounds.