154390-46-2

Upstream product

• 4927-55-3 1,2-bis(3,4-dimethoxyphenyl)ethanone 
• 100-46-9 benzylamine 
• 84675-72-9 1,2-Bis-(3,4-dimethoxy-phenyl)-butan-1-one 
• 75-36-5 acetyl chloride 

Relevant academic research and scientific papers

An improved method for the generation of imines and enamides. Application to the synthesis of 3-arylisoquinoline derivatives

The one-pot preparation of hindered 1,2-diarylethylamines 3 and 4 and ethylenenamides 5 is achieved via sodium cyanoborohydride reduction and acylation of the deoxybenzoin imines 2, respectively. A new methodology for the synthesis of 3-arylisoquinolinium salts by the Bischler-Napieralski reaction of 1,2-diarylethylenenamides and their transformation into 12-methyl substituted benzo[c]phenanthridines has been developed.