154391-75-0Relevant articles and documents
Synthesis And Properties Of Anhydride Of BenzoSelenoxanthene-3,4-Dicarboxylic Acid
Guttsait, A. V.,Balodis, K. A.,Meirovits, I. A.
, p. 1226 - 1229 (1993)
By the reaction of the anhydride of 4-nitronaphthalene-1,8-dicarboxylic acid with 2-aminobenzoselenol zincate, followed by the action of isoamyl nitrite on the reaction mixture, the anhydride of benzoselenoxanthene-3,4-dicarboxylic acid has been synt
Naphthalimide derivative containing selenoheterocycle, and preparation method and antiviral application thereof (by machine translation)
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, (2020/07/12)
The invention discloses a selenoheterocycle-containing naphthalimide derivative and a preparation method and an antiviral application thereof, wherein the naphthalimide derivative is 1. H, 3H-selenium xanthene [2, 1, 9 -]Def] Isoquinoline -1, 3 (2)HThe diketone derivative hydrochloride has a structural formula shown in the formula (1 - 7) as shown in the specification. The compound 1 - 7 disclosed by the invention is used for inducing a human host cell II type serine protease TMPMPMPRSS2 promoter region to be rich in guanine DNA sequences to induce formation G - four-chain bodies. The conjugated mother ring structure in compound 1 - 7 can interact with G - four split formed in the research target in π -pi stacking mode through computer molecule simulation experiment, and the side chain can be well combined with the groove structure G - four-chain body. The invention plays an important role in developing clinical medicine development of the naphthalimide derivative containing the selenium heterocycle, and especially has an important value for finding a new antiviral small molecule medicine. (by machine translation)
