134174-55-3

Upstream product

• 35350-43-7 bis(o-nitrophenyl) diselenide 
• 577-19-5 2-nitrophenyl bromide 
• 51694-22-5 ortho-nitrophenyl selenocyanate 
• 88-74-4 2-nitro-aniline 
• 7440-66-6 zinc 

Downstream Products

• 273-91-6 benzoselenazole 
• 859779-57-0 bis-(2-formylamino-phenyl)-diselenide 
• 859951-86-3 2-picrylamino-selenophenol 
• 2818-88-4 2-methylbenzoselenazole 
• 32586-68-8 2-phenylbenzo[d][1,3]selenazole 
• 109516-28-1 4-(benzo[d][1,3]selenazol-2-yl)-N,N-dimethylaniline 
• 70086-67-8 2-(methylselanyl)aniline 
• 24783-71-9 2-benzoselenazol-2-yl-benzoic acid 
• 24783-70-8 N-benzoselenazol-2-ylmethyl-N-phenyl-glycine 
• 3616-90-8 4H-benzo[1,4]selenazine-2,3-dione 2-[(4-chloro-phenyl)-hydrazone] 
• 77085-28-0 1,4-diazaphenoselenazine 

Relevant academic research and scientific papers

Naphthalimide derivative containing selenoheterocycle, and preparation method and antiviral application thereof (by machine translation)

The invention discloses a selenoheterocycle-containing naphthalimide derivative and a preparation method and an antiviral application thereof, wherein the naphthalimide derivative is 1. H, 3H-selenium xanthene [2, 1, 9 -]Def] Isoquinoline -1, 3 (2)HThe diketone derivative hydrochloride has a structural formula shown in the formula (1 - 7) as shown in the specification. The compound 1 - 7 disclosed by the invention is used for inducing a human host cell II type serine protease TMPMPMPRSS2 promoter region to be rich in guanine DNA sequences to induce formation G - four-chain bodies. The conjugated mother ring structure in compound 1 - 7 can interact with G - four split formed in the research target in π -pi stacking mode through computer molecule simulation experiment, and the side chain can be well combined with the groove structure G - four-chain body. The invention plays an important role in developing clinical medicine development of the naphthalimide derivative containing the selenium heterocycle, and especially has an important value for finding a new antiviral small molecule medicine. (by machine translation)

Compound for treatment or prevention of breast cancer

The invention discloses a compound for treatment or prevention of breast cancer, specifically a 2-phenyl benzoselenazole compound, its pharmaceutically acceptable salt and easily hydrolysable prodrug. The invention further discloses a pharmaceutical composition containing the compounds and use of the compound in preparation of drugs for treatment or prevention of breast cancer in mammals. The compound involved in the invention can effectively inhibit or reduce mammalian breast cancer cell growth or proliferation, at the same time, the compound has no inhibiting effect on the growth of partial test cells except for breast cancer cells and has good selectivity. The compound shows more obvious efficacy, high selectivity, low toxicity and small side effect. (formula of the compound).