154423-34-4

Basic information

• Product Name: 5-[4-[4-(bromomethyl)phenyl]phenyl]-1-trityl-tetrazole
• Synonyms: 5-[4'-(Bromomethyl)biphenyl-4-yl]-1-trityl-1H-tetrazole
• CAS NO: 154423-34-4
• Molecular Formula: C₃₃H₂₅BrN₄
• Molecular Weight: 557.48
• Mol File: 154423-34-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 707.7°C at 760 mmHg
• Flash Point: 381.8°C
• Density: 1.28g/cm³
• Vapor Pressure: 7.11E-20mmHg at 25°C
• Refractive Index: 1.66
• CAS DataBase Reference: 5-[4-[4-(bromomethyl)phenyl]phenyl]-1-trityl-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[4-[4-(bromomethyl)phenyl]phenyl]-1-trityl-tetrazole(154423-34-4)
• EPA Substance Registry System: 5-[4-[4-(bromomethyl)phenyl]phenyl]-1-trityl-tetrazole(154423-34-4)

Safety Data

• Hazardous Substances Data: 154423-34-4(Hazardous Substances Data)

Upstream product

• 1429045-73-7 C₃₃H₂₆N₄ 
• 50670-50-3 p-(p-tolyl)benzonitrile 
• 623-00-7 4-bromobenzenecarbonitrile 
• 31614-66-1 tributyl(p-tolyl)stannane 

Downstream Products

• 1429045-88-4 C₂₃H₁₈N₆S 
• 1429045-86-2 C₂₂H₁₆N₆S 

Relevant articles and documents

Synthesis and evaluation of quinazoline derivatives as phosphodiesterase 7 inhibitors

The latest scientific findings concerning PDE7 and PDE4 inhibition suggest that selective small-molecule inhibitors of both enzymes could provide a novel approach to treat a variety of immunological diseases. In this context, we describe a new series of quinazoline derivatives from quinazolin-4-thiones which include a substituted biphenyl fragment. Some of these compounds show inhibitory potencies at sub-micromolar levels against the catalytic domain of PDE7.