154498-13-2

Upstream product

• 67-56-1 methanol 
• 1346570-22-6 ethyl 2-(4-((trimethylsilyl)ethynyl)phenyl)acetate 
• 14062-25-0 Ethyl 4-bromophenylacetate 
• 63349-52-0 methyl 4-iodophenylacetate 
• 1798-06-7 (4-iodophenyl)acetic acid 
• 154498-12-1 methyl 2-(4-(2-(trimethylsilyl)ethynyl)phenyl)acetate 

Downstream Products

• 1421928-86-0 methyl 2-(4-((2-methylpyridin-3-yl)ethynyl)phenyl)acetate 
• 843662-36-2 methyl 2-(4-(4-hydroxybenzoyl) phenyl) acetate 
• 154498-14-3 3-{3-hydroxy-6-[2-(4-methoxycarbonylmethylphenyl)-ethinyl]-2-pyridyl}-propionic acid methyl ester 
• 1027586-35-1 [(S)-5-[(S)-3-tert-Butoxy-2-(2-{4-[4-(tert-butoxycarbonylamino-methyl)-phenylethynyl]-phenyl}-acetylamino)-propionylamino]-5-(2-cyclohexyl-ethylcarbamoyl)-pentyl]-carbamic acid tert-butyl ester 
• 189132-05-6 (4-{2-[4-(tert-Butoxycarbonylamino-methyl)-phenyl]-ethyl}-phenyl)-acetic acid 
• 189132-04-5 {4-[4-(tert-Butoxycarbonylamino-methyl)-phenylethynyl]-phenyl}-acetic acid 
• 476692-60-1 (4-{4-[3-(4-methoxycarbonylmethyl-phenyl)-cyclobut-2-enyloxycarbonylmethyl]-phenylethynyl}-phenyl)-acetic acid 3-(4-methoxycarbonylmethyl-phenyl)-cyclobut-2-enyl ester 
• 476692-55-4 3-(4-(carbomethoxymethyl)phenyl)cyclobutenone 
• 476692-57-6 3-(4-(carbomethoxymethyl)phenyl)cyclobutenol 
• 476692-53-2 3-(4-(carbomethoxymethyl)phenyl)-4,4-dichlorocyclobutenone 
• 1025975-03-4 {4-[4-(tert-Butoxycarbonylamino-methyl)-phenylethynyl]-phenyl}-acetic acid methyl ester 

Relevant academic research and scientific papers

COMPOUNDS AND METHODS

The present invention relates to novel retinoid-related orphan receptor gamma (RORy) modulators and their use in the treatment of diseases mediated by RORy.

Conformationally constrained [p-(ω-aminoalkyl)phenacetyl]-L-seryl-L- lysyl dipeptide amides as potent peptidomimetic inhibitors of Candida albicans and human myristoyl-CoA:protein N-myristoyl transferase

MyristoylCoA:protein N-myristoyltransferase (NMT) covalently attaches the 14-carbon saturated fatty acid myristate, via an amide bond, to the N- terminal glycine residues of a variety of cellular proteins. Genetic studies have shown that NMT is essential

PYRIDINE COMPOUNDS WHICH ARE USEFUL AS LEUKOTRIENE-B4-ANTAGONISTS

The invention relates to new pyridine derivatives of general formula I which have useful properties, e.g., as leukotriene-B 4-antagonists. Pharmaceutical compositions containing these compounds can be used to treat various diseases.