154557-38-7 Usage
Function
Silylating reagent in organic synthesis
Purpose
Protect hydroxyl groups in chemical reactions
Physical state
Colorless liquid at room temperature
Boiling point
159-161°C
Solubility
Soluble in organic solvents (e.g., ether, chloroform)
Stability
Stable under normal conditions
Application
Preparation of trimethylsilyl ethers
Utility
Useful tool in synthetic organic chemistry
Check Digit Verification of cas no
The CAS Registry Mumber 154557-38-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,5,5 and 7 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 154557-38:
(8*1)+(7*5)+(6*4)+(5*5)+(4*5)+(3*7)+(2*3)+(1*8)=147
147 % 10 = 7
So 154557-38-7 is a valid CAS Registry Number.
154557-38-7Relevant articles and documents
The protection of ketones and aldehydes as 4-trimethylsilylmethyl-1,3- dioxolanes
Lillie,Avery
, p. 969 - 972 (1994)
The 1,3-dioxolanation of carbonyl compounds with 2,3- bis(trimethylsilyloxy)-trimethylsilylpropane (BTTP) in the presence of catalytic amounts of trimethylsilyl trifluoromethanesulfonate (TMSOTf) has been investigated. BTTP readily converted unhindered ketones and aldehydes to their corresponding 4-trimethylsilylmethyl-1,3-dioxolanes, but failed for more hindered substrates. The 4-trimethylsilylmethyl-1,3-dioxolane can be selectively cleaved to regenerate the carbonyl compound in the presence of a 1,3-dioxolane using either LiBF4 or HF in acetonitrile.
