15457-05-3

Usage

Safety Profile

Mildly toxic by ingestion. An eyeirritant. Used as an herbicide. When heated todecomposition it emits very toxic fumes of NOx and Fí.

Metabolic pathway

Photopysis products of eight substituted diphenyl ethers (preforan, nitrofen, MC-338, MC-4379, MC-3761, MC-5127, MC-6063, and MC-7181) irradiated by a Raryonette reactor in solutions of water, cyclohexane, and methanol indicates that the major reaction pathways of these biphenyl ethers include reductive dehalogenation, decarboxyalkylation, reduction of nitro substituents to amines, and cleavage of the ether linkage to yield phenols.

InChI:InChI=1/C13H7F3N2O5/c14-13(15,16)8-1-6-12(11(7-8)18(21)22)23-10-4-2-9(3-5-10)17(19)20/h1-7H

Upstream product

• 100-02-7 4-nitro-phenol 
• 121-17-5 2-chloro-3-nitro-5-trifluoromethylbenzene 

Related news

Metabolism of substituted diphenylether herbicides in plants. II. Identification of a new FLUORODIFEN (cas 15457-05-3) metabolite, S-(2-nitro-4-trifluoromethylphenyl)-glutathione in peanut08/23/2019

The herbicide, 2,4′-dinitro-4-trifluoromethyl diphenylether (fluorodifen), is eleaved in peanut to give the metabolite, S-(2-nitro-4-trifluoromethylphenyl)-glutathione. A comparison of the glutathione conjugate isolated from treated peanut leaves and from in vitro pea epicotyl glutathione S-tra...detailed

Metabolism of substituted diphenylether herbicides in plants. I. Enzymatic cleavage of FLUORODIFEN (cas 15457-05-3) in peas (Pisum sativum L.)08/22/2019

A “soluble” glutathione S-transferase that catalyzes the cleavage of the herbicide, 2,4′-dinitro-4-trifluoromethyl diphenylether (fluorodifen), was isolated and partially characterized from epicotyl tissues of pea seedlings. A 32-fold purification of the enzyme was achieved by differential ce...detailed

Mercapturic acid formation in the metabolism of propachlor, CDAA, and FLUORODIFEN (cas 15457-05-3) in the rat☆08/21/2019

When [14C]F3-fluorodifen (2,4′-dinitro-4-trifluoromethyl diphenylether), carbonyl-[14C]CDAA (N,N-diallyl-2-chloroacetamide), and carbonyl-14C-propachlor (2-chloro-N-isopropylacetanilide) were fed to rats, 57 to 86% of the 14C was excreted via the urine within 48 hr. Although very little radioac...detailed

Metabolism of FLUORODIFEN (cas 15457-05-3) by soil microorganisms08/20/2019

The metabolism of fluorodifen (p-nitrophenyl α,α,α,-trifluoro-2-nitro-p-tolyl ether) by soil microorganisms in the presence or absence of other carbon and nitrogen sources was studied. The degradation of this herbicide continued for 5 days, when benzoate or acetate and ammonium sulphate were ...detailed

Tobacco plants over-expressing the sweet orange tau glutathione transferases (CsGSTUs) acquire tolerance to the diphenyl ether herbicide FLUORODIFEN (cas 15457-05-3) and to salt and drought stresses08/18/2019

The glutathione transferases (GSTs) are members of a superfamily of enzymes with pivotal role in the detoxification of both xenobiotic and endogenous compounds. In this work, the generation and characterization of transgenic tobacco plants over-expressing tau glutathione transferases from Citrus...detailed

Relevant academic research and scientific papers

Halopyridyl triazolinone herbicides and herbicidal use thereof

Disclosed are herbicidal halopyridyl triazolinones, herbicidal compositions comprising the halopyridyl triazolinones, and herbicidal use of the compounds and compositions. Such compounds and compositions are useful as both preemergence and postemergence herbicides in a variety of crops.

Process of improving activity of herbicides and fertilizers using N-(2-hydroxyethyl)-acetamide or -propanamide

The invention is related to the use of certain water-soluble compounds known as such and having the Formula for the modulation of membrane dependent metabolism processes within living cells, in particular with relation to transport phenomena and cell procedures which are induced or influenced by active agents supplied from outside the cell, products containing these substances for the above described uses and processes using these products.

5,6-Dihydro-1,2,4,6-thiatriazin-5-one-1,1-dioxides

5,6-Dihydro-1,2,4,6-thiatriazin-5-one-1,1-dioxides of the formula STR1 where R1 is hydrogen, a metal atom or an unsubstituted or substituted ammonium radical, R2 is a saturated or unsaturated straight-chain aliphatic radical of up to 10 carbon atoms, a cycloaliphatic radical or 3 to 7 carbon atoms, a branched saturated or unsaturated aliphatic radical of 3 to 10 carbon atoms, a halogen-, alkoxy- or alkylmercapto-substituted aliphatic radical of 2 to 10 carbon atoms tetrahydrofuryl substituted methyl, a cycloalkoxy-substituted aliphatic radical of 4 to 10 carbon atoms, unsubstituted or halogen-substituted benzyl or phenyl, halophenyl, or alkylphenyl of a total of up to 10 carbon atoms, R3 is hydrogen, a straight-chain aliphatic radical of up to 10 carbon atoms, a cycloaliphatic radical of 3 to 7 carbon atoms, a branched aliphatic radical of 3 to 10 carbon atoms, haloalkyl, or alkoxyalkyl of 2 to 10 carbon atoms and X is oxygen and may also be sulfur if R2 is unsubstituted or halogen-substituted benzyl, processes for their preparation, and herbicides containing the above compounds.