154669-38-2

Upstream product

• 154669-34-8 1-Benzyl-3-diazo-2,4-pyrrolidindion 
• 75-65-0 tert-butyl alcohol 
• 30125-76-9 1-(phenylmethyl)pyrrolidine-2,4-dione 

Downstream Products

• 154669-40-6 1-Benzyl-1,5-dihydro-3,4-dihydroxy-2-pyrrolon 
• 160621-80-7 1-Benzyl-4-benzyloxy-3-tert-butoxy-1,5-dihydro-2-pyrrolon 

Relevant academic research and scientific papers

Reductones of Tetronic, Thiotetronic and Tetramic Acids, II. - Reductones by Rhodium-Catalyzed Decomposition of Diazo Compounds

The diazoketones 2 have been synthesized by diazo transfer reaction with 2-azido-3-ethylbenzthiazolium tetrafluoroborate.The rhodium-catalyzed decomposition of compounds 2 in tert-butyl alcohol at 130 deg C furnishes the reductone monoethers 3 and after deprotection the aci-reductones 4.Methylation of compounds 4 with diazomethane proceeds stepwise leading first to the monoethers 5 and then to the diethers 6.The thiolactone 4b and even more the lactams 4c and 4d are stronger reducing agents than the lactone 4a. - Key Words: 2,4-Oxolandiones / 2,4-Thiolandiones / 2,4-Pyrrolidindiones / Reductones / Diazo compounds