154706-44-2 Usage
General Description
3-MethoxyMollugin is a naturally occurring chemical compound that belongs to the class of substances known as lignans, which are widely found in plants and have diverse biological activities. It is specifically derived from the plant Rubia cordifolia, known for its medicinal properties in traditional medicine. 3-MethoxyMollugin has been studied for its potential antioxidant and anti-inflammatory properties, making it a candidate for potential therapeutic applications in the treatment of various diseases. Additionally, it has been investigated for its potential anti-cancer effects, particularly in inhibiting the growth and proliferation of cancer cells. Overall, 3-MethoxyMollugin is a compound with promising pharmacological potential and warrants further studies to fully understand its therapeutic properties.
Check Digit Verification of cas no
The CAS Registry Mumber 154706-44-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,7,0 and 6 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 154706-44:
(8*1)+(7*5)+(6*4)+(5*7)+(4*0)+(3*6)+(2*4)+(1*4)=132
132 % 10 = 2
So 154706-44-2 is a valid CAS Registry Number.
154706-44-2Relevant articles and documents
Synthesis of the natural products 3-hydroxymollugin and 3-methoxymollugin
Sastry, Mudiganti Naga Venkata,Claessens, Sven,Habonimana, Pascal,De Kimpe, Norbert
, p. 2274 - 2280 (2010)
(Figure Presented) 3-Hydroxymollugin 2 and 3-methoxymollugin 3 are cytotoxic compounds isolated as minor compounds from Pentas longiflora and Rubia cordifolia. Syntheses of 3-hydroxymollugin 2 and 3-methoxymollugin 3 were developed starting from easily available 3-bromomollugin 6. Surprisingly, it was found that the reaction of 3-bromomollugin 6 with sodium methoxide in methanol resulted in the formation of 3-methoxymollugin 3 and the ring-contracted methyl isopropenylfuromollugin 7. A mechanism for this ring contraction is proposed on the basis of a pericyclic retro oxa-6π ring-opening reaction. A second synthesis of 3-hydroxymollugin 2 was based on epoxidation of methyl 3-(3-methylbut-2-enyl)-l,4-naphthoquinone-2-carboxylate 17 and subsequent reduction of the quinone moiety, ring transformation, and DDQ oxidation. The latter oxidation process results in 3-hydroxymollugin 2 along with the rearranged furomollugin 4, which is a ring-contracted analogue of the natural product mollugin 1.
