154708-63-1

Basic information

• Product Name: methyl 1-amino-2,5-dimethyl-4-<2-(phenylmethyl)benzoyl>-1H-pyrrole-3-carboxylate
• Synonyms: methyl 1-amino-2,5-dimethyl-4-<2-(phenylmethyl)benzoyl>-1H-pyrrole-3-carboxylate
• CAS NO: 154708-63-1
• Molecular Weight: 362.428
• Mol File: 154708-63-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 1-amino-2,5-dimethyl-4-<2-(phenylmethyl)benzoyl>-1H-pyrrole-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 1-amino-2,5-dimethyl-4-<2-(phenylmethyl)benzoyl>-1H-pyrrole-3-carboxylate(154708-63-1)
• EPA Substance Registry System: methyl 1-amino-2,5-dimethyl-4-<2-(phenylmethyl)benzoyl>-1H-pyrrole-3-carboxylate(154708-63-1)

Safety Data

• Hazardous Substances Data: 154708-63-1(Hazardous Substances Data)

Upstream product

• 154708-57-3 methyl 1-tert-butoxycarbonylamino-2,5-dimethyl-4-<2-(phenylmethyl)benzoyl>-1H-pyrrole-3-carboxylate 
• 4755-81-1 methyl 2-chloroacetoacetate 
• 120935-81-1 1-<2-(phenylmethyl)benzoyl>-1,3-butanedione 
• 950203-40-4 methyl 3-tert-butoxycarbonylazo-2-butenoate 
• 55810-66-7 2-(benzyl)benzoyl chloride 
• 61608-94-4 1-(2-(phenylmethyl)phenyl)ethanone 

Downstream Products

• 120934-96-5 methyl 2,5-dimethyl-4-(2-(phenylmethyl)benzoyl)-1H-pyrrole-3-carboxylate 

Relevant articles and documents

Azoalkene route to methyl 2,5-dimethyl-4[2-(phenylmethyl)benzoyl]-1H- pyrrole-3-carboxylate (FPL 64176) and analogues: Synthesis of 1-(BOC- amino)pyrrole-3-carboxylates and their conversion to 1H-pyrroles via 1- aminopyrroles

A new route to the calcium channel activator methyl 2,5-dimethyl-4[2- (phenylmethyl)benzoyl]-1H-pyrrole-3-carboxylate (FPL 64176) and analogues is presented. Reaction of activated diones with BOC-azoalkenes gave pyrroles with the required functionality bu