61608-94-4Relevant academic research and scientific papers
Cobalt-Catalyzed Reductive Cross-Coupling Between Benzyl Chlorides and Aryl Halides
Pal, Suman,Chowdhury, Sushobhan,Rozwadowski, Elodie,Auffrant, Audrey,Gosmini, Corinne
supporting information, p. 2431 - 2435 (2016/08/16)
A new protocol for the direct reductive cobalt-catalyzed arylation of benzyl chlorides has been developed in order to form functionalized diarylmethanes. A variety of reactive groups either on the aryl or the benzyl halide was employed. This represents the first cobalt-catalyzed reductive cross-coupling which does not require any ligand and pyridine. A reaction pathway is proposed involving a radical benzyl species. (Figure presented.).
Bismuth-catalyzed synthesis of anthracenes via cycloisomerization of o-alkynyldiarylmethane
Park, Jungmin,Choi, Hyuck,Lee, Deug-Chan,Lee, Kooyeon
supporting information, p. 7005 - 7007 (2015/11/27)
In this study, anthracenes were efficiently synthesized from o-alkynyldiarylmethane using a novel method that exploits the synergistic effect between Bi(OTf)3 as the catalyst, and trifluoroacetic acid (TFA). Through this reaction, we achieved the rapid and efficient synthesis of anthracenes bearing various functional groups under mild conditions.
PREPARATION METHOD OF ANTHRACENE DERIVATIVES CATALYZED BY BISMUTH SALTS
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Paragraph 0121; 0122, (2017/01/02)
The present invention relates to a method for preparing an anthracene derivative by using a bismuth catalyst. The invention relates to a method for preparing an anthracene derivative simply and efficiently by using a bismuth catalyst and an acid additive. The preparation method allows obtaining a target material in a short time at a high yield by using a bismuth catalyst and an acid additive. Then, the prepared anthracene derivative may be used in a synthesis of intermediate in fine chemicals including pharmaceuticals and agricultural chemicals, and a synthesis of a variety of polymer materials having optical properties.COPYRIGHT KIPO 2015
Flexible and practical synthesis of anthracenes through gold-catalyzed cyclization of o -alkynyldiarylmethanes
Shu, Chao,Chen, Cheng-Bin,Chen, Wei-Xi,Ye, Long-Wu
, p. 5542 - 5545 (2013/11/19)
A concise gold-catalyzed method for the preparation of anthracenes from o-alkynyldiarylmethanes has been developed. Under mild reaction conditions, versatile anthracene derivatives were formed in moderate to good yields. The high flexibility, broad substrate scope, and mild nature of this reaction render it a viable alternative for the synthesis of anthracenes.
Direct method for carbon-carbon bond formation: The functional group tolerant cobalt-catalyzed alkylation of aryl halides
Amatore, Muriel,Gosmini, Corinne
supporting information; experimental part, p. 5848 - 5852 (2010/09/03)
(Figure Presented). A new protocol for the direct cobaltcatalyzed alkylation of aryl halides has been developed that proceeds smoothly in the presence of phosphanes or bipyridines as ligands with a variety of alkyl halides, including challenging alkyl electrophiles bearing β hydrogen atoms (see scheme). Sensitive functional groups are tolerated on both coupling partners, thus, significantly extending the general scope of transition-metal-catalyzed alkylation of aryl halides.
High catalytic efficiency of nanostructured molybdenum trioxide in the benzylation of arenes and an investigation of the reaction mechanism
Wang, Feng,Ueda, Wataru
experimental part, p. 742 - 753 (2009/10/01)
The synthesis and characterization of nanostructured MoO3 with a thickness of about 30 nm and a width of about 450 nm are reported. The composition formula of the MP (precipitation method) precursor was estimated to be [(NH4)2O]0.169·MoO 3· (H2O)0.239. The calcination of the precursor in air afforded nanostructured pellets of the α-MoO3 phase. The nano-structured MoO3 catalyst exhibited high efficiency in catalyzing the benzylation of various arenes with substituted benzyl alcohols, which were strikingly different to common bulk MoO3. Most reactions offered >99% conversion and >99% selectivity to monoalkylated compounds. MoO3 is a typical acid catalyst. However, the benzylation reaction over nanostructured MoO3 does not belong to the acid-catalyzed type or defect site-catalyzed type, since the catalyst has no acidity and defect site on surface. Characterization with thermal, spectroscopic, and electronic techniques reveal that the catalyst contains fully oxygen-coordinated MoO 6 octahedrons on the surface but partially reduced species (Mo 5+) within the bulk phase. The terminal oxygen atoms of Mo=O bonds on the (010) basal plane resemble oxygen anion radicals and act as active sites for the adsorption and activation of benzyl alcohols by electrophilic attack. Such sites are indispensable for catalytic reactions since the blocking of these sites by electron acceptors, such as tetracyanoethylene (TCNE), can greatly decrease catalytic activity. This work represents a successful example of combining a heterogeneous catalysis study with nanomaterial synthesis.
Nanostructured molybdenum oxides and their catalytic performance in the alkylation of arenes
Wang, Feng,Ueda, Wataru
supporting information; scheme or table, p. 3196 - 3198 (2009/02/04)
We report for the first time that nanostructured MoO3 is an excellent catalyst for the alkylation of a wide range of arenes with substituted benzyl alcohols as alkylating agents. The Royal Society of Chemistry.
A molecular balance to measure the strength of N-H?π hydrogen bonds?based on the tautomeric equilibria of C-benzylphenyl substituted NH-pyrazoles
Cornago, Pilar,Claramunt, Rosa M.,Bouissane, Latifa,Elguero, José
, p. 3667 - 3673 (2008/09/21)
A theoretical (B3LYP/6-31G**) study of 30 pyrazoles, most of them existing in two tautomeric forms, has been carried out. 3(5)-(2-Benzylphenyl)-5(3)-methyl-1H-pyrazole (11) and 3(5)-(2-benzylbenzylphenyl)-5(3)-phenyl-1H-pyrazole (20) were synth
Suzuki cross-coupling reaction of benzylic halides with arylboronic acids in the presence of a tetraphosphine/palladium catalyst
Chahen, Ludovic,Doucet, Henri,Santelli, Maurice
, p. 1668 - 1672 (2007/10/03)
The cis,cis,cis-1,2,3,4-tetrakis(diphenylphosphinomethyl) cyclopentane-[PdCl(C3H5)]2 system catalyses efficiently the Suzuki cross-coupling reaction of benzylic halides with arylboronic acids. A wide variety of benzylic bromides or chlorides and functionalised arylboronic acids lead selectively to the corresponding diarylmethane adducts in good yields. Furthermore, this catalyst can be used at low loading in many cases.
Geometry-affinity relationships of the selective serotonin receptor ligand 9-(aminomethyl)-9,10-dihydroanthracene
Runyon, Scott P.,Peddi, Srinivas,Savage, Jason E.,Roth, Bryan L.,Glennon, Richard A.,Westkaemper, Richard B.
, p. 1656 - 1664 (2007/10/03)
With the exception of its two aromatic rings and basic nitrogen atom, 9-(aminomethyl)-9,10-dihydroanthracene (AMDA; 1) is remarkably devoid of the pharmacophore features usually associated with high-affinity receptor ligands such as the heteroatom hydrogen bonding features of the endogenous ligand serotonin. AMDA does contain a phenylethylamine skeleton within a tricyclic ring system, and the presence of the second aromatic group is necessary for optimal receptor affinity. The structural requirements for the binding of AMDA at 5-HT2A receptors were investigated with respect to the geometric relationship between the two aromatic rings. It appears that the geometry of the AMDA parent is in the optimal range for fold angle between aromatic moieties. Evaluation of conformationally constrained derivatives of AMDA suggests that a chain extended trans, gauche form is most likely responsible for high affinity.
