154708-65-3

Upstream product

• 431-47-0 trifluoroacetic acid-methyl ester 
• 61608-94-4 1-(2-(phenylmethyl)phenyl)ethanone 
• 55810-66-7 2-(benzyl)benzoyl chloride 

Downstream Products

• 154708-58-4 4-(2-Benzyl-benzoyl)-1-tert-butoxycarbonylamino-5-hydroxy-2-methyl-5-trifluoromethyl-4,5-dihydro-1H-pyrrole-3-carboxylic acid methyl ester 
• 909914-28-9 3-(2-benzylphenyl)-5-trifluoromethyl-1H-2-pyrazolin-5-ol 
• 909914-25-6 5-(2-benzylphenyl)-3-trifluoromethyl-1H-pyrazole 

Relevant academic research and scientific papers

The structure of pyrazoles in the solid state: A combined CPMAS, NMR, and crystallographic study

The structures of six N-unsubstituted pyrazoles, three already known and three newly synthesized, have been studied by a combination of X-ray crystallography, multinuclear NMR (solution and solid state), and density functional theory (DFT) calculations. I

Azoalkene route to methyl 2,5-dimethyl-4[2-(phenylmethyl)benzoyl]-1H- pyrrole-3-carboxylate (FPL 64176) and analogues: Synthesis of 1-(BOC- amino)pyrrole-3-carboxylates and their conversion to 1H-pyrroles via 1- aminopyrroles

A new route to the calcium channel activator methyl 2,5-dimethyl-4[2- (phenylmethyl)benzoyl]-1H-pyrrole-3-carboxylate (FPL 64176) and analogues is presented. Reaction of activated diones with BOC-azoalkenes gave pyrroles with the required functionality bu