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Carbamic acid, (3-hydroxycyclopentyl)-, 1,1-dimethylethyl ester, (1S-trans)-, commonly known as carbofuran, is an organic compound with the molecular formula C10H19NO3. It is a carbamate insecticide widely used in agriculture for its high toxicity to a broad spectrum of insects and pests, making it an effective tool for crop protection. However, it is also recognized for its potential health and environmental risks, including harm to humans and animals, and its classification as a significant hazard to aquatic organisms. Carbofuran has been associated with neurotoxicity and carcinogenicity, leading to its ban in several countries.

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  • 154737-89-0 Structure
  • Basic information

    1. Product Name: Carbamic acid, (3-hydroxycyclopentyl)-, 1,1-dimethylethyl ester, (1S-trans)-
    2. Synonyms: (1S,3S)-tert-butyl(3-hydroxycyclopentyl)catbaMte;tert-Butyl ((1S,3S);Carbamic acid, (3-hydroxycyclopentyl)-, 1,1-dimethylethyl ester, (1S-trans)-;Carbamic acid, [(1S,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester, rel-;tert-butyl (1S,3S)-3-hydroxycyclopentylcarbamate;tert-butyl N-[(1S,3S)-3-hydroxycyclopentyl]carbamate;(3-Hydroxycyclopentyl)carbamic acid 1,1-dimethylethyl ester;N-[(1S,3S)-3-Hydroxycyclopentyl]carbamic acid 1,1-dimethylethyl ester
    3. CAS NO:154737-89-0
    4. Molecular Formula: C10H19NO3
    5. Molecular Weight: 201.26276
    6. EINECS: N/A
    7. Product Categories: N-BOC
    8. Mol File: 154737-89-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 320.8°Cat760mmHg
    3. Flash Point: 147.8°C
    4. Appearance: /
    5. Density: 1.08g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.486
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. PKA: 12.27±0.40(Predicted)
    11. CAS DataBase Reference: Carbamic acid, (3-hydroxycyclopentyl)-, 1,1-dimethylethyl ester, (1S-trans)-(CAS DataBase Reference)
    12. NIST Chemistry Reference: Carbamic acid, (3-hydroxycyclopentyl)-, 1,1-dimethylethyl ester, (1S-trans)-(154737-89-0)
    13. EPA Substance Registry System: Carbamic acid, (3-hydroxycyclopentyl)-, 1,1-dimethylethyl ester, (1S-trans)-(154737-89-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 154737-89-0(Hazardous Substances Data)

154737-89-0 Usage

Uses

Used in Agricultural Industry:
Carbamic acid, (3-hydroxycyclopentyl)-, 1,1-dimethylethyl ester, (1S-trans)is used as a pesticide for [application reason] its effectiveness in controlling a wide range of insects and pests, thereby protecting crops from damage and increasing agricultural productivity. However, due to its high toxicity and potential adverse effects on human health and the environment, it has been banned in several countries, and its use requires strict adherence to safety regulations and guidelines.

Check Digit Verification of cas no

The CAS Registry Mumber 154737-89-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,7,3 and 7 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 154737-89:
(8*1)+(7*5)+(6*4)+(5*7)+(4*3)+(3*7)+(2*8)+(1*9)=160
160 % 10 = 0
So 154737-89-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H19NO3/c1-10(2,3)14-9(13)11-7-4-5-8(12)6-7/h7-8,12H,4-6H2,1-3H3,(H,11,13)/t7-,8-/m0/s1

154737-89-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl N-[(1S,3S)-3-hydroxycyclopentyl]carbamate

1.2 Other means of identification

Product number -
Other names WT993

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:154737-89-0 SDS

154737-89-0Relevant articles and documents

POLYFLUORINATED COMPOUNDS ACTING AS BRUTON TYROSINE KINASE INHIBITORS

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Paragraph 0374; 0375, (2016/08/17)

Described herein is a novel series of multi-fluoro-substituted pyrazolopyrimidine compounds or salts thereof. These compounds are Bruton's tyrosine kinase (BTK) inhibitors. These compounds may possess better BTK inhibition selectivity and pharmacokinetic properties. Disclosed herein are the synthesis methods of these compounds. Disclosed herein are novel synthesis methods of the multi-fluoro-substituted benzophenone and substituted phenoxy benzene. Also disclosed are pharmaceutical compositions comprising the BTK inhibitors described herein. The present invention also relates to pharmaceutical formulations comprising the compounds described herein as active ingredients. The present invention also includes the therapeutic methods by administering the BTK inhibitors and their formulations to treat and inhibit autoimmune disease, hypersensitivity disease, inflammatory diseases and cancer.

4-CYCLOALKYLAMINOPYRAZOLO PYRIMIDINE NMDA/NR2B ANTAGONISTS

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, (2010/02/11)

Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are effective as NMDA/NR2B antagonists useful for treating neurological conditions such as, for example, pain, Parkinson's disease, Alzheimer's disease, epilepsy, depression, anxiety, ischemic brain injury including stroke, and other conditions.

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